International Conference on Human Genetics and Genomics, آذر ماه ۱۴۰۰

Accepted papers in International Conference on Human Genetics and Genomics

• Improved Vascular Graft in Tissue Engineering by genedelivery

• New challenge of bioethic in human genome project

• Investigation of mitochondrial pathogenesis genes in somediseases caused by mitochondrial defects

• The Importance Genomics and Proteomics in Lung Cancer

• The use of stem cells in restorative medicine

• Polyploid Giant Cancer Cells

• MiRNA in the Diagnosis and Prognosis of Pediatric AcuteLymphoblastic Leukemia

• The function of Circulating microRNAs in pathogenesis ofiron overload in children with Transfusion-Dependent β-Thalassemia major

• CTX۰۰۱ is CRISPR/Cas۹-based treatment to Increasedfetal hemoglobin for Treatment of sickle cell anemia

• TNF-α antagonists have offered benefit in patients withprogressing vitiligo

• Altered Expression of Long non-coding RNAs in AcuteMyeloid Leukemia

• Importance and function of long non-coding RNAs inleukemia

• Epigenetic changes and breast cancer

• Specific targeting of point mutations in ۴ carcinogenicgenes in lung cancer by CRISPR / Cas۹

• Neuroinflammatory State of Multiple Sclerosis andStrategies for Biotherapeutics Development

• Prospects for the Diagnosis and Treatment of Hemophilia A

• The role of lncRNAs as biomarkers in the diagnosis andtreatment of various cancers

• The role of genetics in epilepsy

• Detection and monitoring of cancer using ctDNA andMicrofluidics

• Evaluation of Alzheimer's disease

• Evaluation of the effect of trastuzumab in the treatment ofbreast cancer

• The role of nucleotide repeats in the development ofSpinocerebellar ataxia and Friedrich ataxia

• Achieving the pathogenesis of inflammatory intestine(bowel) disease by tissue proteome

• Investigating the Role of Wnt/Β-Catenin SignalingPathway in Gastric Cancer

• The role of circular RNA in myocardial infarction

• influence of intestinal inflammation using exosomemediators

• The role of LincFOXF۱ in cancers

• Parkinson’s contributed genes analysis

• In vivo-In vitro trials in Developing for therapeuticstrategies of Stargardt disease with desirable future

• The role of Piwi interacting RNAs (piRNAs) in cancer

• Investigation of genes and polymorphisms associated withthe severity of Covid-۱۹

• The effect of ADAM۹ gene on the severity of COVID-۱۹disease

• Gene transfer by viral and non-viral vectors, especiallynanoparticles

• Investigation of sperm genetic quality in causes of maleinfertility and common treatment methods

• Beta Thalassemia Therapy by CRISPR/Cas۹

• Induced pluripotent stem (iPS) cells for modelling ofgenetic disorders

• Editing The Mitochondrial Genome Using The NovelMethod Of DddA

• Role of Gene Therapy for the Treatment of Cancer

• Analysis of diseases caused by hemoglobin deficiency:Sickle cell anemia and thalassemia

• A brief overview of the genes involved in acute lymphoidleukemia

• Comparison of Viral and Non-viral Vectors in GeneTherapy

• An overview to diagnosis and treatment of childhood acutelymphoblastic leukemia (ALL)

• Pharmacokinetics and Pharmacogenomics ofChloroquine and Hydroxychloroquine in the treatment ofCovid-۱۹

• The role of FOXO transcription factors in cancer

• The importance of stem cells in the treatment of cancer

• The effect that genes have on the corona

• Exon-skipping therapeutic approach inDuchenne Muscular Dystrophy

• The role of CRISPR in controlling TNBC using theBRCA۱ and BRCA۲ genes

• An Analysis on The Effect of Polymorphisms on HighBlood Cholesterol among Iranians

• Improvement of beta thalassemia symptoms byexamining the role of polymorphic markers

• Role of three main ABC transporters in multidrugresistance

• The role of LncRNA MIR۲۰۵HG in cancer

• Genetics of infertility and recurrent miscarriage

• Recombinant factor VIII for hemophilia treatment

• The role of LncRNAs in cancer

• Huntington's disease and novel genetic therapies

• The function and importance of Crisper technique in thetreatment of leukemia

• Genetics of cardiovascular disease

• Novel studies on balancing growth and production rate ofvitamin C

• Fighting against sickle cell disease by CRISPR/Cas۹

• The role of long Intergenic non-protein codingRNA۶۶۷(LINC۰۰۶۶۷) in cancer

• FTO gene polymorphism (rs۱۵۵۸۹۰۲) and obesity inathletes and non-athletes individuals

• Evaluation of effective factors in reducing the level ofpain and anxiety in the treatment of pediatric leukemia

• Cryonics in Human

• What Is Hemophilia?

• The FGF/FGFR System and EGFR in Breast Cancer:signaling targeted therapies

• Investigation of genetic mutations in thyroid cancer

• CAR-T Cell Therapy and Expectations

• Gene therapy in type ۱ diabetes

• Thyroid Cancer in the Pediatric Population

• The importance of DNA in molecular and cellular biology

• Interaction of vitamin D with ACE۲ gene expression inmodulating the SARS-COV-۲ phenotype

• The role of stem cells in pediatric leukemia

• Genetics of eye diseases

• A review on specific diabetes gene and inheritance

• Evaluation of gene therapy in thalassemia

• Circular RNAs as New Regulators in Gastric Cancer:Diagnosis and Cancer Therapy

• Diagnostics of lung cancer using next-generationsequencing technology

• Review on the most important gene polymorphismsmodulating serum cholestrol level

• The role of circular RNAs as prognostic and therapeuticbiomarker in triple negative breast cancer

• Study of DNA soluble and DNA Long

• Personalized Medicine: The role of pharmacogeneticbiomarkers in cancer therapy

• Association of FTO gene polymorphisms and obesity

• Application of aptamers in colorectal cancer therapy

• The role of Lnc DA۱۲۵۹۴۲ in colorectal cancer

• Genetic diagnosis and counseling

• Lung Cancer and its Relation to Human MolecularGenetic

• The role and function of exosomes in metastasis

• P۵۳-inactivating mutations introduces a path efficientCRISPR–Cas۹ genome editing

• The effect of gene therapy on the control and treatmentof pediatric leukemia

• Reconstruction of spinal cord injuries by embryonic stemcells

• Effect examination of ozone gas injection and hyaluronicacid in osteoarthritis patients

• long non-coding RNAs in childhood acute lymphoblasticleukemia patients

• Acute lymphoblastic leukemia in children

• Treatment of neurodegenerative diseases by stem cells

• Strategies to overcome drug resistance to imatinib inchronic myeloid leukemia cells

• Investigation of genetic mutations in autism

• Stem Cells in Plastic Surgery: A brief review

• Circular RNAs molecule: The potential target in cancertherapy

• Single Nucleotide Polymorphisms as the EfficientPrognostic Markers in Breast Cancer

• Competition of microbes with antimicrobial peptides andhuman tools for its improvement

• Manipulation and isolation of cells using molecularbeacons and flow cytometry for multi-gene cell lineproduction

• Progression of CRISPR/Cas۹ technology for cancertherapy

• ERK/MAPK signaling pathway function in acutelymphoblastic leukemia

• A review of the association between cancer and Covid ۱۹

• An epigenetic mechanism underlying non-Mendelianinheritance patterns

• A review in Variation Aspect of Cystic Fibrosis (CF)

• Stem cell and cancer stem cell in cancer therapy

• Investigation of the effect of k + sperm channels onsperm motility in humans

• Investigating the effect of sperm tail on their movementin humans

• The role of IGF۱R and GRB۷ genes in targetedtreatment of breast cancer

• Most common form of dementia: Alzheimer

• New applications of PCR

• LncRNAs as potential biomarkers and therapeutictargets for Parkinson’s disease

• MicroRNAs can be used as Biomarkers for EarlyDiagnosis, Prognosis, and Therapeutic Targeting ofOvarian Cancer

• Gene therapy in the treatment of diseases

• Computational Analysis of Notch۱ and its correlated miRNAs Involvedin Colorectal Cancer Progression

• Naringenin and Resveratrol Anti-tumor Impact on the Y۷۹ Retinoblastoma by Affecting E/N-Cadherin and Galectin-۳; PossibleSynergistic Effect

• GJB۲ gene related nonsyndromic hearing loss in Mazandaran Province, north of Iran

• Comparison of CD۴+ and CD۸+ T- lymphocyte in Helicobacter pylorinegative functional dyspepsia

• Comprehensive bioinformatics analysis of mir-۶۱۶ in triple negative breast cancer

• Evaluation of VEGFA mRNA as non-invasive diagnostic biomarker in endometriosis

• Bioinformatics-based analysis of microRNAs as crucial contributors in gastric cancer

• Lesser known factors in having diabetes; focus on: aralkylamine Nacetyltransferase (AANAT)

• The important role of copy-number variations in hereditary spastic paraplegia

• Design of a T-cell epitope vaccine against BKRF۴ protein Epstein-Barr virus in Burkitt's lymphoma using immunoinformatics approaches

• In-Silico Analysis of single nucleotide polymorphisms (SNPs) in PTEN gene associated with T-cell acute lymphoblastic leukemia

• Vanadyl Sulfate has an Apoptotic Effect on MCF-۷ Breast Cancer Cell Line

• A bioinformatics analysis of Runx۱ and its related miRNA Involved in Colorectal Cancer metastases

• SiRNA-mediated knockdown of Nrf۲ gene induces apoptosis of AGS cells

• Increased level of JNK (MAPK) enzyme in anuclear cell (platelet) under osmotic stress

• A Comparative Study of Fluoxetine and Glatiramer Acetate Therapy in the Mouse Model of Multiple Sclerosis

• Bi-allelic variants in IPO۸ cause human importin- β -related disorders

• Analysis of mRNA-miRNA Interaction between Breast Tumor Tissues and Adjacent Normal Tissues

• Evaluation of miR-۳۸۲ expression change in the prefrontal cortex of the brain following alcoholism in male Wistar rats

• Nrf۲ knockdown increases apoptosis of hepatocellular carcinoma cells

• The genetic basis of lactase persistence and lactose digestion in Iran and Afghanistan

• Silencing CDC۲۰ gene by siRNA-loaded nanoniosome in cancer cell therapy

• A bioinformatics analysis of microRNAs related with breast carcinoma specific gene as a biomarker

• BEST۴ and CA۷ as two novel molecular signatures in CRC: a systems biology study

• Exosomes derived from Mesenchymal Stem cells alleviate the expressions of liver Fibrogenic genes in human hepatic stellate cells

• The role of cytosolic Toll like receptor ۲, ۴ in endometrial samples from women with hydrosalpinx

• Evaluation of endosomal Toll-like receptors-۳ and ۹ gene expressions in endometrial of hydrosalpinx women

• Design and amplification of an antimicrobial peptide based on scorpion mucroporin toxin

• The proliferation and migration of metformin-treated vascular smooth muscle cells are suppressed via Focal Adhesion Kinase in high glucose conditions

• Investigation of binding interactions between three active ingredients; Curcumin, γ-Terpinene, and Safranal with BMP ۱۵

• Trehalose reduces the number of Stress Granules in cancer-resistant cells, increasing Sorafenib and Gemcitabine sensitivity

• Study of nettle extract and shigatoxin effects on the inflammation-wound healing process in mouse

• Identification of Survival-Associated Long Non-Coding RNAs Hubs in Papillary Thyroid Carcinoma through Bioinformatics Analysis

• Prevalence assessment of LuxS-dependent quorum sensing system genes in Enterobacteriaceae

• Evaluation of a functional polymorphism in has-miRNA-۱۹۶a۲ (rs۱۱۶۱۴۹۱۳ C/T) with breast cancer risk in west Iranian women

• Thalassemia screening in relative couple: Importance of Prenatal Diagnosis Tests and Genetic Counseling

• In-silico study of rs۳۰۲۵۰۴۰ and hsa-mir-۱۹۹a-۵p single nucleotide polymorphisms related to VEGFA gene in patients with gastric cancer

• Comparison of TRBF peptide structure, in mammals using bioinformatics

• Investigation of genes and pathways involved in breast cancer subtypes through gene expression meta-analysis

• Prevalence of Chromosomal abnormalities in cytogenetic findings of patients studied in Golestan province

• Integrative meta-analysis identifies the involvement of neurotrophin signaling pathway in AML chemo-resistance

• Investigation of the pathogenicity of one of the missense single nucleotide polymorphism in IKZF۱ gene

• Effect of nuclear factor erythroid ۲-related factor silencing on the MiaPac۲ pancreatic cancer cells

• Key genes in neural stem cells differentiation of mouse embryonic stem cells: a comprehensive bioinformatics analysis

• Integrative Analysis of MicroRNA and Gene Interactions Associated with BRAF Gene Mutation in Melanoma

• Impact of Methadone and Morphine on Mental Activity and Gfap Expression in Male Norway Rat

• Association of ART۳ rs۶۸۳۶۷۰۳ polymorphism with non-obstructive Azospermia in Iranian men

• Study of black-cumin on the expression of the genes related to the lipid metabolism in mice

• The improvement of Anti-CD۲۰ Antibody Affinity with site-specific mutagenesis in CDR۳ (Tyr۱۰۱ to Arg)

• The study of expression of CCAT۲-Lnc noncoding gene in HT-۲۹ and HCT-۱۱۶ colorectal cancer cell line with Gemini Curcumin

• Inhibition of miR-۴۲۷۰ in HepG۲ cell line to suppress in-vitro metastasis and invasion

• Expression profile evaluation of Interferon gamma and leptin genes in infertile women compared with fertile individuals

• In silico analysis of identification miRNA-mRNA regulatory network in acute myeloid leukemia (AML) patients

• Expression of Long non-coding RNAs (LncRNA), PWRN۱ in colorectal cancer

• The Role of ccr۵ Receptor in Expression of neat-۱ in Breast Cancer Patients with Positive HIV

• The Study of changes in affinity of Anti-CD۲۰ antibody with mutations Tyr۱۰۱ and Tyr۱۰۷ to Arg in CDR۳ using docking

• Single nucleotide polymorphisms in BRCA۲ partial sequences associated with breast cancer in human

• TXNDC۸ mRNA expression Evaluation in semen of infertile men

• Evaluation of SOS۱ gene mutation in breast cancer and the effect of miR-۱۴۶a-۵p on this gene

• Exome sequencing in the diagnosis of breast cancer

• The effect of remdesivir on differentiation of human mesenchymal stem cells into osteoblast

• PIK۳R۱ targeting by miR-۵۵۷۱-۵p induced tumor progression and invasion in breast cancer

• Bioinformatics analysis of GDF ۱۱ with three common active ingredients from Turmeric, Cumin, and Saffron

• Inhibitory effect of twist۱ antisense oligo-nucleotides on invasion rate of androgen dependent prostatic cancer cells

• Homozygous Deletion of exon ۷ in SMN۱ gene without phenotypic features of spinal muscular atrophy

• Determination of Pathogenic Mutations in NT۵C۲ Gene using Bioinformatics Tools

• The Study of the Pathogenicity of SNPs in MT-ND۳ gene using bioinformatics sites

• The Highest Odd Ratio of SNP rs۷۷۱۸۹۱۹ in Multiple Sclerosis among ۱۰ Variant of IL۷R Gene

• Pathogenicity analysis of G۲۹۷C in GATA۴ gene in non-syndromic Tetralogy of fallot (TOF)

• Computational approaches to design Anti-CD۵۲ Nano body: A new insight for B-CLL and MS therapeutic strategies

• The effects of nano-Curcumin adjuvant therapy in hospitalized COVID- ۱۹ patients

• In-silico evaluation of single nucleotide polymorphisms in PSEN۱ gene in patients with Alzheimer's disease

• Alignment and phylogenetic tree analysis of some corona and influenza type-A viruses based on nucleocapsid protein sequences

• In Silico Analysis of Anti-Microbial Peptides on HER۲ Protein in Breast Cancer

• Bioinformatics evaluation of targetom hsa-miR-۱۴۶a-۳p signaling pathways and related to The IFNAR۲ in COVID-۱۹ patients

• The impact of FAS gene expressions in endometriosis

• In-silico analysis of SHOX Gene for Following Pathogenicity Single- Nucleotide Polymorphisms (SNPs) in Patients with Short Stature Deficiencies

• In-vitro antioxidant therapy and improvement of sperm parameters and quality in asthenoteratozoospermia patients

• Genes contributing to the adverse effects of lithium therapy in bipolar disorder

• In-silico analysis of SNPs in mitochondrial MT-ND۴ gene

• Inferring cell lineage differential gene expression analysis using singlecell RNA-seq

• Long noncoding RNA TP۵۳TG۱ alteration impact on breast cancer progression

• Computational analysis of single nucleotide polymorphisms (SNPs) in human MPO gene

• The influences of chicken embryo extract on the fate of epidermal neural crest stem cells

• Bioinformatics analysis of potential interactions between hsa-miR-۱۴۳- ۵p and E۶ and E۷ mRNAs from HPV-۱۶

• In silico analysis predicting effects of deleterious SNPs of human ETV۶ gene on its functions

• Inhibition of LSD۱ by gsk-lsd۱ small molecule inhibitor stimulates fetal hemoglobin in CD۳۴+ cells

• Introducing prognosis biomarkers of acute myeloid leukemia by weighted gene co-expression network analysis

• Comparative study of expression of non-coding circular RNAs circBIRC۶ and circCORO۱C in cord blood CD۳۴+ stem cells and its differentiated cells

• In vivo identification of novel target genes in colorectal adenocarcinoma by the cDNA-AFLP technique

• Selection of a CD۱۹ specific scfv by phage display with future prospect in CAR-T cell therapy of leukemia cancer

• Investigating differential expression of mTOR۱/UCA۱ in tumor samples of colorectal cancer compared with tumor marginal samples

• Identifying the miRNA and mRNA‑associated networks to reveal potential prognostic biomarkers for Breast cancer

• Evaluation of the Effect of Ni on Expression Changes of NKILA in leukemia

• Molecular and prenatal diagnosis in retinoblastoma affected family: findings from Next-Generation Sequencing

• Assessment of lead heavy metal on the genome of E. coli

• In vitro and Drosophila models of rare monogenic disorders

• H. pylori and its cagA gene Prevalence in gastric cancer or peptic ulcer patients at in Qom

• Reconstruction of Hippo Signaling Pathway Co-Expression Network in AML

• Evaluation of apoptosis induction in HepG۲ cell line by inhibition of miR-۴۲۷۰

• Investigate the association of ۲۶۵۰۰۰۰ and ۶۵۴۴۷۱۴ polymorphisms in the ABCG۸ gene with high cholesterol

• In Silico analysis identification of long noncoding RNAs associated with genes involved in response to trastuzumab antibody treatment in gastric cancer cells using microarray data

• Effects of cytotoxic concentrations of ibuprofen on BAX, BCL۲ gene expression in cervical cancer cells (HELA)

• Evaluation of genetic variants of exon ۷ of SPATA۶ gene in infertile men with acephalic spermatozoa syndrome

• MMP-۲ enriching protein-protein and functional interaction networks in neurogenesis and neural stem cells differentiation

• Can Recombinant Cryptococcus neoformans HSP۷۰ be a Candidate for Developing an ELISA Kit?

• Molecular modeling of Wuhan SARS-CoV-۲ RBD in complex with ferritin nanoparticle

• The Impact of Single-Nucleotide Polymorphisms rs۸۵۲۹۷۷ of NR۳C۱ Gene on Depression in North of Iran

• Autism and FOXP۲ gene involved

• Integrated analysis of gene expression profiles of T-lymphocytes in human T cell leukemia virus type ۱ (HTLV-۱) associated disease: A bioinformatics analysis

• Regulatory T lymphocytes, the pivotal role in inhibiting GVHD

• Study of injury and involvement related to lung squamous cell and adenocarcinoma caused by miRNA-۴۸۶ in children with Duchenne muscular dystrophy

• Network-based Prediction of microRNAs targeting RdRp and N coronavirus-۲ genes

• Clinical, radiological, and genomic characteristics of mitochondrial leukodystrophies in Iran

• Impact of oxidative stress SNPs on sperm DNA damage and male infertility

• In silico polyepitope vaccine design against SARS-COV-۲ infection

• Pathogenic analysis of R۴۵۶C mutation in the GATA۶ gene in atrial septal defect (ASD)

• In silico design and evaluation of signal peptide for secretory expression of interferon a۲b in E. coli

• Bachelor's thesis in plant orientation biology coronavirus

• Non-invasive screening of G۳۷۰C, S۲۴۹C and R۲۴۸C mutations of FGFR۳ gene in urinary epithelial cells in patients with bladder cancer

• The expression profiles and prognostic values of Annexin family genes in breast cancer

• A study of associations between DROSHA (rs۱۰۷۱۹), DICER (rs۳۷۴۲۳۳۰), RAN (rs۱۴۰۳۵) and XPO۵ (rs۱۱۰۷۷) polymorphic variants and recurrent pregnancy loss in Southeast Iranian women

• Gene expression analysis of Parvovirus B۱۹ in primary and continuous cell lines

• The synergistic cytotoxic and apoptotic effect of resveratrol and Naringenin on Y۷۹ retinoblastoma cell line

• In silico Molecular docking of lead nitrate interaction with replication compounds of E. coli

• A functional evidence for ATF۷IP association with human intellectual disabilities

• Study of Silibinin effect on PTEN in human breast cancer cell line

• GJB۲ Polymorphism rs۷۳۲۹۸۵۷ is associated with autosomal recessive non-syndromic hearing loss in Iranian population

• Bioinformatics evaluation of targetom has- miR-۵۱۳a-۳p signaling pathways and related function of SOD۱ in patients with amyotrophic lateral sclerosis

• In-silico analysis of Site Direct Mutagenesis of Tyr۱۰۲ to Arg in CDR۳ of Anti-CD۲۰ antibody

• Ki-۶۷ marker and neurotrophic genes expression in metformin-treated mesenchymal stem cells in ۴۸ hours

• In silico study of association of has-mir-۵۶۹۸ with COVID-۱۹ severity in diabetics

• A case report of a man with Klinefelter Syndrome having healthy two Neonates with normal karyotype

• The Affinity optimization of Anti-CD۲۰ antibody with site-directed mutagenesis of Tyr۱۰۷ to Arg۱۰۷ in CDR۳ region

• Construction and affinity enhancement of a new anti-CD۲۰ single-chain variable antibody fragment

• Bioinformatics study and evaluation of neurotoxin botulinum A optimized gene expression as a vaccine candidate

• Pathogenicity analysis of missense mutations in MT-ND۶, a mitochondrial gene that encoded NADH dehydrogenase ۶

• Potential biomarkers and signaling pathways associated with the pathogenesis of primary salivary gland carcinoma: A bioinformatics study

• Social work and infertile women

• Suppressive effect of Gemini Curcumin on the expression of LncRNA CCAT۲ AGS gastric cancer cells gastric cancer

• Association study rs۳۸۱۰۶۸۸ of NLGN۴ gene with Autism spectrum in an Iranian population

• Evaluation of miR-۲۰۰a expression pattern in the blood of non-small cell lung cancer patients compared with normal individuals

• Evaluation of the plasma levels of LncRNAs as biomarker for late-onset Alzheimer’s disease

• Bioinformatics’ analysis of microRNA in angiogenesis pathway of breast cancer: biomarker role of microRNA

• Unravelling the molecular mechanism of miR-۱۲۸ in oligodendrocyte differentiation

• Genetic variants of Cystic Fibrosis disease in Azeri Turkish population

• Predicting biomarker microRNAs for differentiating ER/PR positive and negative breast cancers using bioinformatics

• Investigation of the role of LncRNA TTTY۱۴ in colorectal cancer using Real-time PCR

• Exploration of potential key genes in oral squamous cell carcinoma by gene network analysis

• Silibinin inhibits MCF۷ breast cancer cell proliferation and migration by GREB۱ targeting

• Association between DROSHA rs۶۴۲۳۲۱ polymorphism and breast cancer in Iranian women

• Key genes associated with the progression of non-small cell lung adenocarcinoma in smokers and non-smokers

• Creating an Efficient Strain for Purity of TEV-Labeled Recombinant Proteins

• Investigation of the subscriptions and association of biologic pathways involved in recurrent acute coronary syndrome

• Structural and conformational studies of loop VI in copper–zinc superoxide dismutase by site-directed mutagenesis

• Epiregulin gene expression profiling in cumulus cells is reflective oocyte/embryo competence and potentially reliable predictor of embryodevelopmental competence in PCOS patients

• Critical roles of extracellular matrix genes in the pathogenesis of carpal tunnel syndrome

• ORF۸: Promising Target Protein for COVID-۱۹ Treatment

• A prion-derived peptide can protect SH-SY۵Y neuroblestoma cells against Aβ۴۲ oligomer cytotoxicity without interaction between the twopeptides

• The effect of crocin on caspase ۶ gene expression in breast cancer

• Novel anticancer peptide derived of Lactoferricin-B inhibits chemo-drug metabolism in cancer cells by blocking GSTP۱ factor

• Analysis of TCGA data of genes and key pathways indicates potential role of histones in breast cancer

• Reanalysis of exome sequencing data in ۲۰ negative hearing loss samples: efficiencies and benefits

• Virtual high throughput screening: potential inhibitors for SARS-CoV-۲ structural and nonstructural proteins

• Over expression of LncRNA DUXAP۸ in gastric cancer tumoral tissues

• Evaluation of miR-۷۴۴ expression pattern in the blood of non-small cell lung cancer patients compared with normal individuals

• Evaluation of breast cancer cell line due to treatment with vitamin E

• Aberrant expression of circ-۰۰۷۲۳۰۹ in breast carcinoma as a promising biomarker for diagnosis

• Effects of motility Sperm and prediction of IUI success

• To study diabetic neuropathy: using transgenic zebrafish model

• RNA sequencing revealed potential biomarkers in Iranian children with B-cell acute lymphoblastic leukemia

• Effects of DNA methylation on serum triglycerides level: A systematic review and meta-analysis

• Association of genetic polymorphism of ۵HTTLPR with temperament in Persian medicine

• rs۱۰۷۱۹ polymorphism in DROSHA gene may destroy binding site of has-miR-۶۶۴a-۳p and has-miR-۱۲۹۸-۵p

• Investigation of LNC HOTAIR in renal cell carcinoma and expression of this LNC

• Molecular docking study of some antiviral drugs against SARS-CoV-۲ RNA-dependent RNA polymerase protein

• Bioinformatics evaluation of targetome LncRNA HOTAIR signaling pathways and related function of miR۱۲۹-۵p in breast cancer

• Bioinformatics analysis of Iranian medicinal plants in the treatment of brucellosis

• Significant association of BRCA۱, BRCA۲ and TP۵۳ gene polymorphisms with breast cancer risk in Khyber Pakhtunkhwa, Pakistan

• Investigation of Lnc DA۱۲۵۹۴۲ expression in colorectal cancer

• Comparison study of MeICT expression in pET۳۲-Rh and pET۳۲a cloning vectors

• The effect of Crocin on breast cancer

• Evaluation of GAB۱ role in pediatric B-cell acute lymphoblastic leukemia

• Alterations in the genes expression profile of hematopoietic stem cell lead to pediatric B-cell acute lymphoblastic leukemia

• Effects of HAMP gene polymorphism on iron over load β-Thalassemia Iraqi patients

• A post-mortem diagnosis of infantile-onset Pompe disease in an Iranian family

• Novel frameshift mutation in SLC۱۲A۲ gene associated with severe phenotype of Allan-Herndon-Dudley syndrome (AHDS)

• Design and cloning of recombinant antimicrobial peptide Melittin-IMekn۲

• Meta-analysis of chronic gastritis developing into gastric cancer by gene expression profiles

• In-silico analysis of pathogenic SNPs in JAG۱ gene

• TT genotype at rs۴۵۱۶۰۳۵ is associated with increased susceptibility to osteoporosis in South-Eastern Iranian people

• The anti-proliferative effect of Moringa olifera aqueous leaf extracts on acute lymphoblastic leukemia cells

• Investigation of changes in the expression of pro-inflammatory cytokines caused by extract Silybum marianum L. in in-vitro and in-vivo

• Investigation of LincNRAV expression in colorectal cancer

• Study of NGF, PAX۳, and NSE genes expression in bone marrow-derived mesenchymal stem cells after treatment by Glabridin for differentiation into nerve-like cell

• Investigation of frequency of VKORC۱ gene polymorphisms in Warfarin treated patients in Rafsanjan

• Design of a common vaccine against influenza and SARS-COV-۲ viruses by using In Silico tools

• Protective effect of HLA-E*۰۱۰۱/*۰۱۰۳ genotype in survival of patients after allogeneic hematopoietic stem cell transplant

• Design of a SNaPshot assay for simple and cost-effective detection of six variant related to recurrent pregnancy loss

• Identification of prognostic biomarkers in papillary thyroid cancer and developing non-invasive diagnostic models through integratedbioinformatics analysis

• The relationship between eNOS gene expression and patients with type ۲ diabetes and depression

• Pancreatic cancer and the effect of MALAT۱ Lnc on it and the level of expression of this Lnc

• Analysis of CFTR gene variants and clinical presentations in children with idiopathic bronchiectasis and unknown etiology

• Study of PHOX۲B, ELP۱ and MAP۲ genes expression in bone marrowderived mesenchymal stem cells after treatment by Glabridin for differentiation into nerve-like cell

• The study of miR-۱۵a and BACE۱ gene expression in patients with Alzheimer's disease

• Evaluation of high cholesterol rs۲۹۶۷۶۰۵ and rs۶۷۵۶۶۲۹ polymorphisms of RAB۱۱B and ABCG۵ and ABCG۸ genes in Isfahan population

• The evaluation of IRSp۵۳ expression in colon cancer patients

• In-silico study of rs۱۸۰۱۱۵۷ and hsa-mir-۱۴۹-۵p single nucleotide polymorphisms related to CLCX۱۲ gene in patients with leukemia

• Potential biomarkers and signaling pathways involved in helicobacter pylori-induced gastric cancer: A network-biology approach

• Biological connections between AHR gene and the genes involving in human skin aging

• Gene Cloning of Omega ۶ Fatty acid as an Effective Dietary Supplement in Cancer Prevention in Yeast host

• Study of ZNF۸۰۴A and DISC۱ Genes in Iranian Patients with Schizophrenia

• The importance of NFATc۱ in endometriosis: a case-control study

• Investigation of Ins۲ gene expression change in polycystic ovary syndrome in mouse model

• PARP۱ expression in sporadic triple-negative breast cancer using bioinformatics analysis

• Identification of crucial genes and pathways associated with esophageal squamous cell carcinoma based on weighted gene correlation network

• Investigating the relationship between gene expression level of MYC gene and non-coding RNA lnc-mycbp-۱-۳ in Acute Lymphoblastic Leukemia

• Bioinformatics evaluation of hsa-miR-۲۰۵-۵p signaling pathways and related function of tp۵۳ in patients with pancreatic cancer

• The elevation of Pinkbar expression in samples of Iranian patients with colon cancer

• Expression of HAND۲-AS۱ in Colorectal Cancer Is Under Control by DNA Methylation

• Identifying novel biomarkers in hepatocellular carcinoma by weighted gene co‐expression network analysis

• Comparison of two computational online tools for sgRNA designing in gene editing experiments by CRISPR/Cas۹

• Association between catalase gene (CAT) and other involving genes in human skin ageing

• Investigation of the Association of FOLH۱ rs۶۱۸۸۶۴۹۴ and DISC۱ rs۱۲۱۳۳۷۶۶ loci in Iranian Schizophrenia Patients

• The expression analysis of has-circ-۰۰۰۰۲۸۴ in breast carcinoma: Looking for a diagnostic biomarker and a possible therapeutic target

• Study of BDNF gene expression in Alzheiemerʹs patients

• Evaluation of the association of XRCC۷ rs۷۰۰۳۹۰۸ gene polymorphism in children with lymphoid cancer

• In-silico analysis of Rac۱ gene and hsa-mir-۱۸۲-۵p and its related target gene of Liver Cancer

• Introducing a recurrent mutation in a patient affected with Methylmalonic academia by Whole Exome Sequence

• Association between rs۹۳۴۴ polymorphism of cyclin D۱ gene (CCND۱) on breast cancer in Iran

• Bioinformatic analysis and Protein Properties of Delta ۶ desaturase Enzyme Cloned in Pichia pastoris

• Pathogenic Analysis of R۴۱۴C Mutation in the APC Gene in FAP Cancer

• Case-Control Analysis of rs۹۳۷۳۰۱ Polymorphism in GIP Correlated to Type ۲ Diabetes in Iranian Population

• Investigating the Pathogenic Single Nucleotide Polymorphisms of MTND۵ Gene by Bioinformatics Tools

• Identification of Potential Substrates for the Enzyme Sortase in the Human Genome

• LC۳B as a novel marker for diagnosis of cancer

• Alignment and phylogenetic tree analysis of CCNE۱ and CCNE۲ cyclic protein partial gene sequences in human

• Application of gene expression sequencing in COVID-۱۹ pandemic diagnostics

• Evaluation of DNA expression of nuclear factor kB (NF-kB) in oral squamous cell carcinoma patients using RT-PCR

• Study of effect of extract of Capparis on expression genes of self-renewal in MCF۷ cells

• In-silico analysis predicting the status of pathogenic SNPs of the human PAX۳ gene

• The effect of Composol Medium on platelet microRNAs expression during blood bank storage

• Psammplysin F increased chemotherapy sensitivity to Doxorubicin by reducing the number of Stress Granules

• In-silico analysis of single nucleotide polymorphisms (SNPs) in human ALK gene

• Analysis of pathogenic SNPs of NOTCH۱ gene using bioinformatics tools

• Evaluation of point mutation of T۵۴R superoxide dismutase enzyme using bioinformatics methods

• Bioinformatics evaluation of expression CK۱۹ gene with miR-۳۰a in breast cancer

• Profiling the expression of LncRNAs involved in colorectal cancer progression in search for suitable diagnostic biomarkers

• Production of optimized AAVs carrying the RPGR gene for X-linked retinitis pigmentosa type-۳ gene therapy

• Evolutionary Trade-offs during tumor progression using Pareto Task Inference (ParTI) analysis

• Differential gene expressions of CALM۱, PSMD۶, and AK۱۲۴۷۴۲ long non-coding RNA in Cumulus cells from PCOS patients vs. normal control women

• The evaluation effects of estrogen on DLGAP۵ gene expression in prostate cancer-۳ (PC۳) cell

• The effect of alpha lipoic acid on cell survival and fis۱ gene expression in a Parkinson's disease cell model

• Pathogenicity prediction of PTS: c.۷۰C>G (p.H۲۴D) variant, identified recently in an Iranian PTPS patient

• Evaluation of alternations in Akt Gene expression in the T۹۸G cell line treatment (Ni)

• The potential effect of miR-۱۷-۵p on RRMS through inhibition of PTEN in CD۴+ T-cells

• The application of gene expression analysis by ART in the selection of competent genes for pregnancy prediction

• Investigation of LincMTX۲ expression in colorectal cancer

• The KLK۲ gene function in prostate cancer through informatics study

• A bioinformatics analysis of A۱۶۸D Substitution in the DMD Gene in Duchenne muscular dystrophy

• A novel missense mutation (c.۲۱۵G>A) in two Iranian siblings with combined oxidative phosphorylation defect type ۷: A case report

• Frequency of MRPA, PGP gene in drug resistance in Leishmania tropica and Leishmania major

• Expression oscillation of natural antisense transcripts in the circadian clock

• Study of the effect of PRKDC knockout on the function of ectodermal genes in mouse embryonic stem cells

• Construction of an LncRNA-miRNA-mRNA network reveals functional Circulating miRNAs in pancreatic cancer

• The significant expression of P۴۵۰ drug metabolism pathway between untreated tumors and normal-adjacent tissues in breast cancer patients

• The evaluation effects of estrogen on BAX gene expression in prostate cancer-۳ (PC۳) cell lines

• Experimental verification and bioinformatics analysis of miRNAs for the differentiation between HER۲ positive and HER۲ negative Breast cancer

• Significance of circulating miR-۱۰۷ in type۲ diabetes mellitus

• Nurr۱/GPX۱-expressing adipose-derived stem cells cultured on PCL/MWCNT scaffolds differentiate into dopamine-secreting cells: A new approach for Parkinsons’s disease cell therapy

• Classification of a PTS gene variant, c.۴۰۰G>A (p. E۱۳۴K), based on ACMG-AMP criteria

• Bioinformatics study of the important role of S۱۰۰A۸/۹ and inhibition microRNA-۲۲۳ in acute myeloid leukemia inflammation and secondaryinjuries

• Predicting of miR-۱۴۹ Regulatory Network and hub genes in breast cancer: an in silico study

• Bioinformatics analysis Identified miR-۴۸۷a-۳p in human dilated cardiomyopathy

• REG۴, CEACAM۵ and OLFM۴ are among the most recurrently fused genes in patients with colorectal cancer

• Occupation of ACE receptor by SARS-CoV-۲ and male infertility risk: An in silico analysis

• Molecular evaluation of exon ۲۸ von willebrand factor gene in the diagnosis of type ۲B VWD in patients referred to the Iranian BloodTransfusion Organization

• Bioinformatically design of potential cyclooxygenase-۱ (Cox-۱) inhibitors

• Comprehensive meta-analysis and differential network analysis of breast cancer

• Molecular docking of secondary metabolites in the plants of apocynaceae family to inhibit P-Glycoprotein (Pgp) for cancer treatment

• Association between common HLA alleles and GVHD occurrence after allogeneic hematopoietic stem cell transplantation

• An Iranian long chain-۳-hydroxyacyl-CoA dehydrogenase deficiency patient with HADHA mutations: case report

• A network-based approach to uncover the potential genes, microRNAs and pathways in colorectal cancer pathogenicity

• Investigation of LincFOXF۱ expression in colorectal cance\

• Identification of the distinctive genes in the development of very early and late relapsed childhood ALL

• Investigating the effect of MMP-۱ gene and its rs۱۷۹۹۷۵۰ polymorphisms on endometriosis disease in an Iranian women population

• In-silico screening of bio-antimicrobial peptides as potential drug for inhibiting CYP۵۱ in Aspergillus fumigatus, Candida albicans and Leishmania infantum

• Correlations of mRNA-miRNA interaction between tumor and margin tissues in patients with breast cancer

• In silico investigation of putative G-quadruplex-forming regions in spike sequence of SARS-CoV-۲ Delta variant

• Novel functionally validated L-asparaginases with anti-proliferating activity against leukemic cell line: A MetaGenomic survey in Caspian Sea

• Effect of alterations in miR-۴۸۳-۳p expression on the expression of SMAD۴ gene in breast cancer patients

• Silibinin inhibits cell migration through downregulation of RAC۱ gene expression in highly metastatic breast cancer cell line

• Investigation of homologous chromosome recombination for immunotherapy in colon cancer

• Pathogenicity analysis of E۲۳۴A mutation in the CITED۲ gene in Ventricular septal defects (VSD)

• Pathogenic Analysis of one of the missense SNP in the F۹ Gene in Hemophilia B

• Mutations in the Delta ۶ desaturase gene by UV and genetic analysis and comparison of GLA production in the mutant and wild strains of Mucor rouxii

• Investigation of LincTNS۱ expression in colorectal cancer

• Twist۱ antisense oligo nucleotides and inhibition of invasion in advanced prostatic cancer cell line

• Investigation of associated between coronary artery disease risk and mir-۱۴۶a (rs۲۹۱۰۱۴۶) polymorphism in an Iranian population

• PEAR۱ genetic variants in Essential Thrombocythemia: The prevalence and association with hematological parameters and ET mutations

• Mutational screening through comprehensive bioinformatics analysis to detect C۲۵۰T mutation in TERT promoter region among patients with brain tumor

• Genomic and ancestral variation underlies the severity of COVID-۱۹ clinical manifestation in individuals of European descent

• Bioinformatics analysis of hsa-miR-۱۳۳a-۳p target genes in Colorectal Cancer process