the fourth International and 16th National Genetics Congress, فروردین ماه ۱۳۹۹

Accepted papers in the fourth International and 16th National Genetics Congress

• Evaluation Of VEGF And FGF Gene Expression Of Chicken'sEmbryo Angiogenesis Affected By Doxycycline Antibiotic

• Inferring Genetic Architecture of Chicken Genome Using the Brand-New Omnigenic Model

• A causative mutation in TAC۱ promoter region is associated with excitability trait in Belgian Malinois dogs

• The role of magnesium sulfate on PPAR-γ and NFKB genes expression in muscle to improve hyperglycemia in STZ-induced diabetic rat

• Genome-wide association study for post weaning weight traits in Lori- Bakhtiari sheep

• Physlr-mol: Physical Map of Linked-reads for De-Novo Barcode to Molecule Deconvolution

• WiNGS: Widely integrated federated platform for analyzing whole

• Emerging roles of the Hippo signaling pathway in cisplatin-resistant ovarian cancer cells

• Targeting of CXCR۱ with Ketoprofen as a novel therapeutic approach for bipolar and schizophrenia diseases

• In silico identification of VDR as a new potential target of Thymoquinone

• A New Reference miRNA IN TUMOR AND NORMAL BREAST TISSUES

• Predicted novel microRNAs located in human IGF۱R gene using bioinformatic analysis

• Comparative expression of ncRNAs in Psoriasis Plaque by bioinformatics method

• GHK-Cu,is it a potential peptide for genocosmetics?

• A genome-wide methylation profiling of a meta cohort dataset to predict biological age using reproducing kernel Hilbert spaces and Bayesian ridge regression

• Proper patient management and genetic testing in diagnosis of Autism Spectrum Disorder

• Anticancer Effect of Gemini Nanocurcumin in Colon Cancer Cell Lines

• Gemini-Curcumin improves the efficacy of cisplatin on breast cancer cells through Bax and Bcl-۲

• The effect of Kat۲a depletion on Ctcf and Myc binding in MLL-AF۹ model of AML

• A novel homozygous frameshift insertion mutation in the RPE۶۵ gene causes autosomal recessive Retinitis pigmentosa

• Synergistic Anticancer Effects of Nano-encapsulated Artemisinin-Chrysin on hTERT gene expression in human Breast Cancer T۴۷D Cell line

• Multiplex genome modifications of astrocytes through CRISPR dead Cas۹: A novel candidate therapy for chronic ischemic stroke

• Expression and function of C۱orf۱۳۲ long-noncoding RNA, in breast cancer cell lines and tissues

• Relationship between expression levels of RPS۶KB۱ and GLI۱ with DYRK۱B during adipogenesis of ADSCs in the presence and absence of R۱۰۲C mutation in DYRK۱B gene

• Investigating the effects of miR-۱۳۸ replacement on inhibiting cell migration and induction of apoptosis in breast cancer cell line

• Investigating the distributions of three common variants of TLR۹ and its mRNA expression levels in NAFL patients without and with liver fibrosis compared to healthy controls

• Effect of omega-۳ compound on gene expression in cancer

• Effect of Escherichia Coli Infection on Semen Sample Exosomes

• Premature Coronary Artery Disease due to Familial Hypercholesterolemia: a genetic based study

• SnO۲ Nanoparticles induced apoptosis in Human Cervical cancer cells

• DNA damage induced by Nucleostemin depletion, along with autophagy abolish differentiation blockage in KG۱a leukemia cells

• PGT-M by using SNP markers: ۵ years of experience

• Registry of Heritable White Matter Disorders in Iran: Clinical, Radiological and Molecular Study of Patients with Classic Leukodystrophies and Genetic Leukoencephalopathies

• Methylation and expression of MyoD۱ gene in breast cancer tissue blocks

• Assessment of MTHFR gene promoter methylation pattern in essential hypertensive patients

• The application of molecular genetic testing in cardiovascular diseases

• Knockdown of long non coding RNA of LINK-A suggests a potential oncogenic function in a۵۴۹ non-small cell lung carcinoma

• iNOS suppression in LPS-induced THP-۱ cells by ethanolic kernel extract of Persian Walnut

• New synthetic peptide inhibitors for targeting autophagy in cancer cells

• Functional and quantitative proteomic analyses of human iPSC-derived RPE and ۳D retinal organoids provide insights into the mechanism of retinitis pigmentosa type ۱۱ and its therapeutic strategies

• A novel mutation in GJA۱ gene in an Iranian Family with non-syndromic congenital heart disease; Detection by whole exome sequencing

• Repair genes expression of mouse cyclophosphamide chemotherapy in Repairing Sperm DNA Fragmentation inside Oocytes

• Prediction of Metabolic Syndrome Based on Genetic Risk Score of HDL and TG Using the Reference-Free GBLUP Model; Tehran Cardiometabolic and Genetic Study (TCGS)

• The association of the ۴۹۷۷ bp sperm mitochondrial DNA deletion with asthenozoospermia in Guilan province of Iran

• Non-invasive prenatal diagnosis of beta-Thalassemia

• O-۴۶ Screening and mutagenesis of the potential microbes to enhance the conversion of Poultry Slaughterhouse

• Effect of Non-Thermal Atmospheric Pressure Plasma on the Expression of Green Fluorescent Protein in Pichia pastoris

• Investigating the Efficiency of BOX-PCR & ERIC-PCR Molecular Markers in Evaluation of the Genetic Diversity of Pectobacterium carotovorum subsp. carotovorum Strains in Different Hosts in East Azarbaijan

• Comparative Metagenomics of the Prokaryotic Communities of the Persian Gulf

• PET biodegradation

• Knockdown of GRP۷۸ gene expression by over expression of miR-۱۸۱a in human bladder cancer cell line; ۵۶۳۷

• Targeting signaling pathways of VEGFR۱ and VEGFR۲ as a potential target in the treatment of breast cancer

• An Inventive Report of Inducing Apoptosis in Non-Small Cell Lung Cancer (NSCLC) Cell Lines by Transfection of MiR-۴۳۰۱

• Designing, construction and functional analysis of SFN۰۰۱۱ as a possible next generation antiangiogenic molecule.

• The effect of miRNA- ۴۴۲۲ replacement therapy in porolifretion, apoptosis,metastasis and migration of KATO Ш cell line in vitro.

• Using of aptamer as a novel molecular tool for neutralizing endotoxin and its effect on platelet factors in animal model

• Production of specific recombinant antibody fused to alkaline phosphatase for direct detection of fig mosaic virus

• A new piRNA-based biomarker for the HER۲ status in breast cancer

• A new aptamer for glioblastoma diagnosis and treatment

• Nucleic Acid aptamers in cancer therapy

• Cytotoxicity and genotoxicity of nanoparticles and drug nancariers

• The Need for Nanosafety to Ensure Human Health and Environmental Safety

• Background and Aim: Gene therapy has become a promising remedy to treat disease by

• Nanomaterials and Immune cells; A Battle Arena Where Both Win

• Toxicity of Metal and Metal Oxide Nanoparticle: Emphasis on Proteomes and Genome

• From nano-formulation toward randomized clinical trial of nano-curcumin on multiple sclerosis patients (a pilot study)

• Respiratory toxicity of nano airborne particulate matter

• The question of genetic safety for Nano materials

• Evaluation of Genetic Diversity in Different Basil Lines (Ocimum basilicum L.)

• Sequence and expression analysis of Anethum graveolens prenyltransferase gene

• Relationships between yield and related traits yield in melon under drought stress using principal factor analysis

• Identification and chromosomal localization of B chromosome-specific repeats in Festuca pratensis Huds.

• Effect of drought stress on antioxidant activity, phenolic and flavonoid content of Artemisia sieberi

• The complete chloroplast genome of Onobrychis gaubae (Fabaceae - Papilionoideae): comparative analysis with related IR-lacking clade species

• Virus Vector-Based Expression of Anti-VEGF Recombinant Protein in Chenopodium Quinoa Plants

• Different k-mer strategies and de novo assembly tools challenge for transcriptome analysis of Citrullus colocynthis (L.)

• Evaluation of molecular diversity of rice varieties in Central and West Asia using microsatellite markers

• Differential expression of microRNAs at the last stage of hepatic differentiation of mesenchymal stem cells

• Delivery of miRNA to brain cancer cells by the secreted exosomes from mesenchymal stem cells as a new method of cancer therapy

• Study of gene flow across Sylvia curruca complex taxa (Passeriformes; Aves)

• Population genetic structure evaluations of the Iranian horse breeds by SSR and SNP markers

• An evaluation of the role of curcumin on Bad gene expression and apoptosis in hippocampus and the behavior of diabetic rat

• The effect of prenatal lead on the expression of Synapsin gene in the hippocampus of ۱۷ day fetal mice

• Design and construction of a gene network associated with ovarian development and evaluation of the effect of phenytoin and venlafaxine on gene expression shift in the designed network.

• The effect of R۱۰ fraction of garlic extract on the expression of Bmp۱۵ and Gdnf۹ genes in PCOS model mice

• Estimation of (co)variance components and genetic parameters for the growth curve characteristics of Iranian Moghani sheep

• Study of genetic association for growth traits in a commercial broiler line and indigenous chicken population

• Genetic improvement in growth traits of first generation hybrid lambs due to crossbreeding of Romanov ram with native sheep of Lori breed

• The effects of high doses of vitamin E on histological alteration in liver of male pups from rat

• Genome-wide detection of copy number variations (CNVs) in Afghan Baluchi sheep breed using Ovine ۵۰k SNPChip array Abstract

• Computational Analysis of Transcription Factors and Gene Networks Using Honeybees (Apis mellifera) Infected with Nosema ceranae Disease Data

• Investigation of ATPase۶ gen polymorphisms in Sanjabi sheep breed

• Crossbreeding effect on GDF۹ and FecB gene SNPs and their protein structure

• Investigation of polymorphism of DGAT۱ gene and its association with body size and tail dimensions traits in Sanjabi sheep

• Allelic and genotypic frequencies of HLA-G upstream polymorphism rs۲۷۳۵۰۲۲ and association with recurrent spontaneous abortion in the northwest of Iran women population

• Study of inbreeding in the inbred population of Holstein cow in Iran

• Effects of mRNA ۵′ cap in protein expression in mammalian cells

• Effect of diabetes mellitus on a specific LncRNA in Hippocampus and Prefrontal cortex

• Conservation of Avian Glucagon has break by c.۲۰۹C>G p.۷۰T>S mutation only in two separate avian orders

• The co-amplification of conserved numts mask the divergent mitochondrial D- loop gene

• Estimation of genetic parameters and inbreeding depression on biometric traits of Iranian Moghani sheep

• New insight on the taxonomic identification of Clinopodes flavidus (Geophilomorpha, Geophilidae) using genetic data

• Estimation genetic trend for reproductive traits in Holstein heifers inseminated with sex-sorted semen.

• Identification of Potential Hub Genes and Regulatory Network in Hepatoblastoma using Transcriptomic Analysis

• In silico assessment of lignin biosynthesis genes in Arabidopsis thaliana and Zea mays

• Identification of Key Transcription Factors in Pancreatic Cancer Using Network Analysis

• Isolation of important MicroRNAs (miRNAs) of basil under abiotic stresses and investigation of the network on the interaction of their targeted genes

• Designing shRNA Targeting ۲۰۱۹-novel Coronavirus RdRPs Gene as a Potential Gene Therapy Tool Using Computational Pattern

• Bioinformatics Analyses of Single Nucleotide Polymorphism rs۳۹۸۱۲۲۵۱۳ in BAX gene in apoptosis

• The response of murine embryonic fibroblast to abnormal expression of Yamanaka factors

• Predicting responses to cisplatin based on zFiltering of the Gene Signature in ovarian cancer

• Bioinformatics evaluation of hsa-miR-۱۳۹-۵p signaling pathways and its associated rs۵۶۲۰۲۴۱۹ function in patients with acute myeloid leukemia

• Bioinformatic Identification of key pathways and hub genes targeted to a panel of signature miRNAs in Diffuse large B-cell lymphoma

• Bioinformatics Analyses of Single Nucleotide Polymorphism rs۳۹۸۱۲۲۸۰۷ in THBD gene in Recurrent pregnancy loss (RPL)

• Antigenic epitopes indentification of Vibrio cholerae surface proteins and designing an its expression cassette

• A bioinformatics analysis of exosomal microRNA released by breast carcinoma: Looking for a diagnostic biomarker

• Predicting miR-۹۹a target genes and identifying key pathways and hub genes in breast cancer using bioinformatics analysis

• Signaling Enrichment Pathway Analysis of Targetome of microRNAs Whose Expression Are Changed in Natalizumab-treated Multiple Sclerosis Patients

• Computational approach to gene expression analysis between Triple Negative Breast Cancer and lung cancer metastasis

• Bioinformatics Prediction of rs۱۰۴۸۹۴۰۹۹ Pathogenicity in CDKN۲A Gene as a Tumor Suppressor Gene (TSG)

• TGFβ signaling pathway as an important pathway in Hypertrophic Cardiomyopathy disease by in-silico analysis

• In Silico Analysis on the Structural and Functional Impact of one deleterious SNP in nkx۲.۵ gene Associated with Congenital Heart Disease (CHD)

• Designing ۲۶S Proteasome Activating Peptides

• In Silico Analysis on Structural and Functional Effect of a Deleterious SNP of CHEK۲ Gene Associated with Prostate Cancer

• Whole-Genome analysis to detect SNPs in some honeybee (Apis mellifera) subspecies using Whole genome sequencing Data

• Evaluation of the role of TGFβ, a-SMA and FGF۱ genes in scar formation during wound healing

• Gene expression profiles and pathway enrichment analysis of Non-small cell lung cancer

• Bioinformatics studies of the anti-cancer effect wild type and mutant E۹K brazzein in docking with TLR۵

• The Possible Regulatory Mechanism of SLCO۱B۱ Expression

• The comparison of interactions between lncRNAs MEG۳ and lnc-EFNB۳-۱ with P۵۳

• investigation of transcriptome response in sorghum bicolor under drought stress by bioinformatics approach

• In silico analysis of key genes and signaling pathways targeted by a panel of signature microRNAs in Hodgkin lymphoma

• In Silico Identification and Annotation of LOS۲ Gene in Walnut (Juglans regia)

• Bioinformatic analysis of key genes and pathways for Lung cancer as a therapeutic target

• Differential gene expression analysis in high oil and low oil maize (zea mays) using RNA-seq data

• Bioinformatics analysis of genes related to pathogenesis of alopecia universalis

• Bioinformatics analysis of CD۲۷۴ expression in triple negative breast cancer

• In silico pathway and network-based analysis to identify potential gene therapy targets for inflammatory bowel disease

• Bioinformatics analysis to introduce novel long non-coding RNAs involved in tamoxifen resistance in breast cancer cells

• In-silico Analysis for Pathogenicity Prediction of Single Nucleotide Polymorphisms in Human LMO۱ Gene

• In silico biomarker prediction for clear cell renal cell carcinoma

• Designing a Ligand-Like Protein for Blocking of TIM-۳

• Bioinformatic studying of the miRNA-mRNA related pathways in brain metastatic breast cancer

• Bioinformatics analysis of differential expression Long non-coding RNA MALAT۱ and related important miRNAs in Tamoxifen-resistant breast cancer cells

• Bioinformatics Analyses of Single Nucleotide Polymorphism rs۲۲۹۳۰۲۴ in TDGF۱ growth factor gene in Congenital Heart Disease

• RNA-Seq data analysis found HDAC, SUZ۱۲ and EZH۲ as the most important Epigenetic regulating factors for generating cardiac progenitor cells through direct reprogramming strategy

• Bioinformatics evaluation of the target signaling pathways and function of hsa-miR-۲۲۱-۳p on rs۲۶۰۳۷۵۱ SNP within NR۴A۱ gene, associated with triple-negative breast cancer

• Evaluation the mechanism of binding of CLF۳۶ chimeric peptide to DnaK and OmpC into the surface proteins in Gram-negative bacteria using computer-based methods

• Bioinformatics study of anticancer activity for wild and mutant A۱۹K brazzein

• Design of novel ABCG۲ inhibitor derivative of anticancer peptide affecting receptor in breast cancer: in silico study

• Insilico Studies and Homology Modeling of a Mesophilic Mojavensis Keratinase

• Bioinformatic Analysis of aflR sequences belonging to some Aspergillus species

• In Silico Analysis of Noncoding SNPs of Human SOCS۳ Gene and their effects on protein functions

• Study of Hypericin effect on microRNAs Expression Level in MCF-۷ Breast Cancer Cells Using microRNA Sequencing

• In-silico analysis of molecular association between Inflammatory Bowel Disease and colorectal cancer

• Bioinformatic analysis to predict small non-coding RNAs as potential biomarkers for HER۲ positive breast cancer

• Single nucleotide polymorphism affects the minimum free energy of miR-۶۱۳: A Bioinformatic analysis

• Molecular Docking study of COVID-۱۹ MPro with Secondary Metabolits of Ginkgo Biloba

• In silico study of HSP۹۰ gene family in zea mays, sorghum bicolor, Glycine max and Hordeum vulgare

• Comparative phylogenetic evaluation of wound healing mechanisms in some organisms

• The effect of metformin on the expression of neurotrophic genes in mesenchymal stem cells

• In-silico analysis to investigate altrations in the secondary structure of miR-۳۱۸۸ due to single nucleotide polymorphism

• Identification and characterization analysis of Ascorbate Peroxidase (APX) and Glutathione Peroxidase (GPX) Gene families in rapeseed (Brassica napus L.)

• Studying of the interaction of tumstatin with some receptors by molecular docking simulations

• In Silico Analysis of Noncoding SNPs of Human FOXD۳ Gene and their effects on protein functions

• Transcriptomic analysis reveals regulatory aspect of drought tolerance in barley spike

• Targeted delivery of L-Asparaginase II into ALL cells using chitosan based nanoparticles and studying the expression of apoptosis-related genes

• Genetic Analysis of the D-LOOP Region of Mitochondrial Genome in Iranian Patients with Familial Adenomatous Polyposis (FAP)

• The study of miR-۳۲۰a expression in multiple sclerosis patients in Zanjan

• Cell cycle disruption of a human cell line using MT۷

• Molecular analysis of magnetic activated sperm sorting in level and expression level of apoptotic micro RN in oligospermia patients

• Noninvasive fetal sex determination in maternal plasma using Multiplex PCR

• Investigation of Eryngium billardieri extract on PPARa gene expression on colon cancer

• Whole exome sequencing detected the main contributor to Atrial Fibrillation in an Iranian family

• MiR-۲۰۵ expression is altered in Breast cancer

• A preliminary approach for designing an Iranian population based genetic panel for early diagnosis of susceptibility to premature ovarian insufficiency

• A new Peter's anomaly causative gene identified

• Evaluation of high-resolution melting method as a powerful technique for the detection of BRAFV۶۰۰E mutation in FNA samples in Papillary thyroid carcinoma

• Competition of miR-۴۵۱ in Breast Cancer using RT-Qpcr

• Study of target genes and key pathways for dysregulated microRNAs in mammosphere with breast cancer stem cells

• RBPJ downregulation is associated with tumor stage and grade in gastric cancer

• Relationship between family history of gastric cancer (GC) and risk of cardia and non-cardia GC in Ardabil province

• Association of rs۳۵۸۲۹۴۱۹ polymorphism of NLRP۳ gene with type ۲ diabetes mellitus

• Evaluation of the expression of RSBN۱L-AS۱ Long non-coding RNA in breast cancer and its relationship with clinicopathological information and reproductive factors

• Study of miR-۳۴۲-۳p expression profile in human breast cancer

• A piRNA as a biomarker for the HER۲ status in breast cancer

• Gemini curcumin suppresses ovarian cancer OVCAR-۳ cells proliferation via induction of apoptosis

• A Novel Mutation in a Patient with Cystinosis

• Carrier frequency of p.R۳۶۸H in glaucoma causing gene CYP۱B۱ may justify pre-marital screenings in eastern Guilan

• Interleukin ۲۱ expression in patients with lupus

• Aberrant expression of circulating miRNAs (miR-۱۴۰ and -۱۹۳b) in colon carcinoma patients Vahideh Javadian-Ghal’e۱, Roudabeh Behzadi Andouhjerdi۱, Sadegh Babashah۲, Ardeshir Hesampour۱, * ۱Department of Biology, Central Branch, Islamic Azad University, Tehran, Iran ۲Department of Genetics, Tarbiat

• In silico analysis of microRNAs involved in the mitochondrial pathway of apoptosis and their role in diabetes-induced memory disorder

• Determination of tumor MSI status without the need for matching normal DNA by analysis of quasimonomorphic markers in Iranian CRC patients

• Molcular detection of G۱۶۹۱A in the factor ۵ Leiden and and its relation with TNF−α gene polymorphisms in abortion human.

• Association of FTO rs۹۹۳۹۶۰۹ Gene Polymorphism with Insulin Resistance in Iranian individuals with Newly Diagnosed Type ۲ Diabetes

• To study anticancer effect of Syzygium cumini in HT-۲۹ colorectal cancer cell line in approach to Bax and bcl۲ genes

• Investigation of single nucleotide variations in exon ۶ of AURKC gene in aneuploid aborted fetuses of women younger than ۳۶ years

• The evaluation of LncRNA GAS۵ expression in type۲ diabetic patients

• A novel mutation in DST gene cause HSAN-VI and mental retardation

• Confirmation of human metastasis in the xenograft nude mouse model: new application for STR typing

• miR-۳۳۱ is correlated with Breast cancer

• In silico analysis of microRNAs expression in spermatogenesis pathway

• Assosiation between rheumatoid arthritis and bladder cancer via TH۱۷ cells

• Investigation of long non-coding RNA LINC۰۰۹۶۱ expression in luminal subtype of breast cancer

• Evaluating the expression of HOTAIR lncRNA in esophageal cancer tissues compared with human's normal tumor margin tissues

• Association between insertion / deletion polymorphism of angiotensin converting enzyme (ACE) gene and risk of glioblastoma cancer in patients referred to Imam Khomeini Hospital in Tehran

• Evaluation of DNA methylation pattern in TLR۲ gene promoter in blood samples derived from PCOS patients

• Assessing the presence of tax and LTR genes in subjects infected with the Human T-cell lymphotropic virus type ۱ (HTLV-۱)

• Evaluation of PER۴ sequence length as the only pseudogene in the molecular clock

• Genetic analysis of rare congenital muscular dystrophy disorders: A three-year cohort study

• non-invasive detection of prostate cancer using miR-۲۵ expression level in patients urine in compared with normals.

• Association of SOCS۱ -۱۴۷۸ CA/del polymorphism with coronary artery disease

• Investigation of single nucleotide variations in exon ۳ of AURKC gene in aneuploid aborted fetuses

• Genetics heterogeneity and novel genes in Hereditary Spastic Paraplegia

• CDH۱ germline mutation in hereditary diffuse gastric cancer: a multicenter study

• Epigenetic effects of melatonin on breast cancer cells in in vitro experiment

• A case of Fraccaro syndrome: Clinical features, cytogenetics, FISH and QF-PCR study.

• Studying the expression of HOTAIR in blood samples of high grade colorectal cancer patients compared with normal people

• Investigation of a Novel LncRNA MCM۳AP-AS۱ gene expression in breast cancer

• Investigation of rituximab clinical response in multiple sclerosis patients

• Changes expression of TMEM۱۶A in infertile men with sperm motility problems

• Investigation of chromosomal abnormalities in men with non-syndromic non-obstructive azoospermia

• Microarray data analysis and Association between IL-۲۷ rs۱۵۳۱۰۹ Polymorphism and the Risk of Bladder cancer in a sample of Iranian population

• A new compound heterozygote mutation in cystic fibrosis

• Antibacterial Effects Studu of Nanofluid Containing Carbon Nanotubes on Pseudomonas Aeruginosa Infections

• The ANRIL exons differentially expressed in premature coronary artery disease

• Optimization of ctDNA extraction of APC gene in blood of patients with Colorectal Cancer

• Evaluation of relationship between HOTAIR gene and breast cancer

• Genotyping of ۳۴ SNP informative autosomal marker for use in the genealogy of Zoroastrian populations in Iran

• Association between LAG-۳ (rs۱۹۹۲۲۴۵۲ G > C) polymorphism and immune thrombocythopenic purpura in Iranian population

• Investigating the effect of Iranian rice bran extract on the expression of PPAR-alpha gene and morphological changes of adipose tissue cells in model mice

• Association of HLA-DRA gene with Non-obstructive azoospermia in Iranian infertile men

• SNPs with a probable role in over-expression of FAIM۲ and prediction of related molecular networks

• Bioinformatics analysis of common mutations in the single gene-form of Parkinson's disease

• Gene delivery of LAMB۳ to cultured keratinocyte cells and produce packaging cell line

• Investigation of anti-epileptic drugs effects on genes expression changes associated with development of male mice gonads

• Aberrant expression of miR-۴۵۱۶ in breast cancer tissue and its correlation with clinicopathological factors

• An association study of miR-۱۲۵b in breast cancer in Isfahan province of Iran

• Bi-directional extremism of the ZMYM۳ gene expression in schizophrenia

• Thrombotic proteins and recurrent abortion

• A case-control study of LINC۰۰۹۶۸ expression in breast cancer

• Clinical and molecular profile of an Iranian patient with homozygous mutation in LARP۷ gene leading to Alazami syndrome

• Association Analysis Between the rs۱۸۹۹۶۶۳ Polymorphism of HOTAIR and Risk of Psychiatric Conditions in an Iranian Population

• Bioinformatically predicted miRNAs regulate the expression of TTN and MYBPC۳ genes

• Adverse effects of bacterial LPS on expression levels of inflammatory genes during chicken fetal development

• A novel non-coding RNA in pancreatic cancer

• Expression analysis of a circular RNA, hsa_circ_۰۰۰۱۶۶۶, in the blood of breast cancer patients before and after chemotherapy

• The comparison of expression circ Amotl۱/hsa_circ_ ۰۰۰۴۲۱۴ as a biomarker in breast cancer tumor tissues and bloods of patients with breast cancer and non tumor tissues and normal bloods

• Autosomal dominant hereditary spastic paraplegia (AD-HSP), the SPAST gene variations and evidence for anticipation

• Whole Exome Sequencing (WES) revealed a novel mutation in KRT۱۰ gene associated with Epidermolytic Hyperkeratosis

• The effect of low-level laser therapy on growth rate and proliferation of mouse embryonic fibroblasts and evaluation of gene expression changes in growth and inflammatory factors involved in wounds healing

• Mir-۳۷۵ suppresses, and OIP-۵ AS۱ shows to trigger Metadherin oncogene expression in different stages of epithelium ovarian carcinoma.

• hsa_circ_۰۰۰۸۷۱۷/circABCB۱۰ expression analysis in peripheral blood of breast cancer patients pre and post chemotherapy in order to find potential biomarker related to response to treatment

• A Case report study of Shah-Waardenburg Syndrome in consanguineous family

• Novel mutations in NF۱ gene in two unrelated patients affected by Neurofibromatosis

• Mutational screening by whole exome sequencing in an Iranian family with Alström syndrome

• Evaluation of the effect of thiosemi carbazone complex Ni on expression changes of CASC۲ lncRNA in controlling of Notch signaling pathway in jurkat E.۶.۱

• Knock down of SIRLNT by Antisense LNA GapmeRs and evaluation of its inhibitory effect on apoptosis and necrosis in human breast cancer cells

• PAX۸ gene expression analysis in thyroid neoplasm

• Association of rs۹۶۳۷۲۳۱ Polymorphism as a Risk Factor with Colorectal Cancer

• Upregulation of miRNA-۲۰۲ leads to apoptosis and inhibits migration and invasion of glioma cell lines through targeting the ROCK۱ gene

• MLH۱ Gene expression and Pathologic factors in Iranian patients with Colorectal Cancer

• Study of the effect of Gemini Curcumin on the expression of pluripotency genes in HCT۱۱۶ colon cancer cells

• Identification of a novel mutation in PLOG in a patient with Progressive external ophthalmoplegia: a case non report

• Compound homozygous mutations in LDLR and PCSK۹ genes cause premature CAD in a family

• The Importance of Genetic Diagnosis of Infectious Diseases

• Investigation of relationship between changes in expression of oncogene LINKA in acute lymphoblastic Leukemia cell line Jurkat E۶.۱ under treatment with ۶MP chemotherapy drug.

• Single locus and haplotypic impacts of GRIN۲B gene with autism spectrum and its demographic and clinical features in Guilan province.

• Anti-cancer effect of a new toxin from Odontobuthus doriae scorpion on breast cancer cell line

• Two novel mutations in the MECP۲ gene associated with typical Rett syndrome

• Genetic studies on patients affected with six related neurodegenerative diseases

• Assessment of HER۲ gene variant expression status in Breast Cancer

• A novel mutation in XPC genee causing xeroderma pigmentosum complementation group C

• Long non-coding RNA H۱۹ in bipolar disorder

• Evaluation of the expression of NPTN-IT۱ Long non-coding RNA in breast cancer and its relationship with clinicopathological information and reproductive factors

• Synthesis and evaluation of pDNA-Loaded liposome for gene delivery to cancer cells

• The role of HERV and EMT in the development of breast cancer

• VEGFR۱, miR-۱۹b, and miR-۹۲a as potential molecular targets in anti- angiogenic therapy of cancer

• Association of chromosome ۹ heteromorphism with Recurrent Pregnancy Loss

• Study of miR-۳۲۰a and its target genes IGFR and RAB۵β for prognosis of insulin resistance in women with polycystic ovary syndrome

• A new long non-coding RNA in pancreatic cancer

• Detection of a new pathogenic mutation on COL۷A۱ gene associated with autosomal recessive Dystrophic Epidermolysis Bullosa

• A new mutation in TCAP gene causing limb girdle muscular dystrophy in a young patient

• ANRIL Variants Are Associated with Risk of Neuropsychiatric Conditions

• Investigating expression level of some genes involved in production of ROS and apoptosis in sperm before and after separation with MACS

• Comparison of the expression profile of miR-۴۹۰-۵P transcripts in healthy samples with Glioblastoma multiforme tumor using MicroRNA sequencing

• A novel mutation in AGL gene causes Glycogen storage disease type III

• Czech dysplasia caused by a novel missense mutation of COL۲A۱ gene

• Homozygous nonsense mutation in the SH۳TC۲ gene causing charcot marie tooth type CMT۴C

• Study of Hypericin effect on Long noncoding RNAs Expression pattern in MCF-۷ Breast Cancer Cells Using RNA Sequencing

• Prevalence of BCR-ABL۱ mutations and clinical outcomes in Iranian patients with chronic myeloid leukemia on imatinib

• Assessment performance of immune systems and genetics factors in patients with cardiovascular disease

• The Effect of oral magnesium sulfate administration on blood SIRT۱ expression in patients with Atherosclerosis

• The evaluation effects of estrogen on DLGAP۵ and ANGPT-۲ genes expression in prostate cancer-۳ (PC۳) cell lines

• Association study between polymorphisms in MIA۳, SMAD۳, SELE, CETP, LIPG and tRNAThr genes, and Coronary Artery Disease (CAD)

• KDM۶A Mutation deregulates translation and nonsense mediated mRNA decay pathways in Intellectual Disability patients

• The value of Fibroblast Growth Factor ۱۰ and novel FGF۱۰AS as a prognostic biomarker in colorectal cancer patients

• Up-regulation of hsa-miR-۵۵۸۴-۵p in breast cancer and association with lymph node metastasis and higher grades

• Impact of polymorphisms in CYP۳A۵ and CYP۲D۶ genes and smoking on imatinib response, cytogenetic relapse in patients with chronic myeloid leukemia on imatinib

• New polymorphism associated with GlanzmannThrombastenia

• Expression analysis of CD۲۴ and CD۴۴ transcripts in Iranian breast cancer patients

• The study of effect of propolis extract on Beta-catenin gene expression in Gastric Adenoma Carsinoma cell line AGS

• Evaluation of alternations in AkT gene expression in the T۹۸G Glioblastoma cell line under treatment with thiosemicarbazones complexes (Ni)

• Thr Expression Profile Evaluation of MIR-۱۲۵B as a Common MiRNAs Between Tuberculosis and Non-Small Cell Lung Cancer

• Haplotype-based association study of Opioid Receptor Kappa-type ۱ (OPRK۱) gene polymorphisms with nicotine dependence

• Value of multiplex ligation-dependent probe amplification technique in determining HER۱-۴ genes alterations in invasive breast cancer

• Higher risk of Multiple Sclerosis based on IL-۴ Gene variations amongst some cohorts of Iranian patients

• Association of rs۷۹۷۵۲۳۲ SNP with the risk of multiple sclerosis

• The effect of Mitochondria-targeted antioxidant on human sperm function and DNA fragmentation

• Silencing of MGMT expression by CRISPR system to better effect of TMZ in GBM patient

• A novel in-frame deletion in the KCNQ۱ gene and an AKAP۹ variant in Iranian patients with long-QT syndrome

• Evaluation of alternations LncRNA CACS۲ expression in the T۹۸G Glioblastoma cell line under treatment with thiosemicarbazones complexes (Cu)

• Detection of Cucumber mosaic Virus (CMV) from Parsley by One-step RT-LAMP

• Evaluation of two factors on hyaluronic acid production by mutant strain of Streptococcus equisimilis by response surface methodology

• The study of linoleic acid and Nanoparticles effects as inducers on Astaxanthin production and Astaxanthin metabolic pathway Genes (CRTO and CRTR) in Haematococcus lacustris

• Cloning and expression of Xylose Dehydrogenase in E.coli

• Genetic diversity of Candidatus phytoplasma aurantifolia using single-strand conformational polymorphism analysis and sequence analyses of the groupII intron gene

• Effects of Sampling Days and Critical Levels of CdCl۲ on Glycerol Production of Dunaliella salina

• Identification of contaminated juice microorganism by ۱۶s rRNA sequencing and decontamination by PEF

• Molecular identification and screening of bioactive actinomycete from soil for enzymatic and antifungal activities

• The meaningful change in Antibiotic-resistant gene expression of Staphylococcus aureus by using functionalized carbon nanotubes Nanofluid

• Molecular detection of Burkholderia gladioli in saffron fields of Khorasan Razavi province

• Molecular Diagnostics of Candida albicans -Secreted Aspartyl Proteinase Genes from women’s urinary tract infections yeast agent in Sari City

• Isolation, cloning, expression and purification of alpha-conotoxin PnIB from the cone snail Conus pennaceus of the Persian Gulf

• Identification of Host Specific Protein Pattern in Mycoplasma gallisepticum pMGA۱.۲ protein

• Bacterial endosymbionts and sex-ratio deviation in predatory mite Ambelyseius Swirski (Acari: Phytoseiidae)

• Cloning and expression of the mutated Exo-Inulinase gene from Aspergillus niger ۵۰۱۲ in E. Coli

• Antimicrobial Resistance Patterns and Plasmid Profiles of Staphylococcus aureus in Burn Patients of Amir-Al-Momenin Hospital, Shiraz

• Cloning and Expression of Human Serum Albumin (HSA) in Escherichia coli

• The expression of gyrI in E. coli strains in the exponential phase of growth

• Evaluation of Bacterial Diversity in Cystic Fibrosis Respiratory Samples via PCR-DGGE and its Comparison with Culture Results

• Curcumin reduces the expression of ahyI, quorum sensing gene, in A. Hydrophila

• Molecular Diagnostics of Candida albicanse Secreted Phospholipase B Genes, Yeast, Popular Vaginal Infectious Agent in Women in Tehran City

• The significant change in Antibiotic-resistant gene expression of Acinetobacter baumannii by using functionalized carbon nanotubes Nanofluid

• Evaluating toxic effects of biosynthetic nanocurcumin on human gastric cancer cells

• The effect of metformin treatment on the gender and mortality of diabetic mice offsprings

• Cloning and expression of BDNF protein in Escherichia Coli

• Viability assessment of human colon and gastric adenocarcinoma cells after treatment with nano-MgO

• Predicting a miRNA as potential biomarker in breast cancer diagnosis thorough bioinformatics analysis

• AMH gene expression level is promoted in the sertoli cells obtained from a patient with prostate cancer orchiectomy

• How Runx-۲ gene is expressed in Sinusoidal Electromagnetic Field pretreated bone marrow-derived mesenchymal stem cells

• Resistant to Inhibitor Cholinesterase gene expression regulation using miR-۹

• Investigation of enterokinase light chain cloning and expression in Escherichia coli

• Anticancer potential of Euphorbia Tehranica Ethyl Acetate Extract against SW۴۸۰ Colorectal Cancer Cell Line

• Investigation of recombinant Lactate Dehydrogenase Expression using SUMO fusion tag

• Analysis of RNA Polymerase Beta Subunit (rpoB) Gene Sequences to discriminate Brucella melitensis Genotypes in Clinical Iranian Isolates

• Study of the vitality of frozen blastema tissue

• Investigation of CD۴۴ (C۳۵۳۶۴۷G and -G۱۸۷۱۱۶A) Gene Polymorphisms in the Benign Prostatic Hyperplasia: A Case-control Study

• Apoptosis Inducing Effect Of Spiroaminopyrimidine Analogue In NB۴ Leukemia Cells Via Down-Regulation Of BIRC۵ Expression

• Evaluating the expression level of ER-α۳۶ in gastric cancer tissue

• Simultaneous effect of CoCl۲-induced hypoxic condition and Thymoquinone treatment on the expression of Sox۲ gene in the cancerous MCF-۷ cell line

• Analysis of Interleukin-۱۰ Gene Polymorphisms in Patients with Idiopathic Chronic Urticarial in East-Azerbaijan

• Investigation of Malate dehydrogenase cloning and expression in Escherichia coli

• Down-regulation of Survivin involved in copper (II) phenylthiosemicarbazone complex-induced apoptosis in leukemia stem-like KG۱a cells

• Expression and functional analysis of LINC۰۰۵۱۳ in colorectal carcinoma tissue and cell lines and its association with Wnt signaling.

• Association study of the CD۳۳ rs۳۸۶۵۴۴۴ polymorphism in Alzheimer's disease (AD) in the Northern Iranian population

• Cytochalasin H cytotoxic effect on human malignant glioma cell line (U۸۷MG) and PLAU and PCDH۱۰ genes expression

• Purification and refolding of recombinant Interferon alpha-۲b over-expressed as inclusion bodies in Escherichia coli

• Investigation of Simultaneous effect of GTP and Ara-C on ATG۵ expression in NB۴ cells

• Investigation of structural and functional properties of mnemiopsin۲ mutant (F۱۹۰L) after immobilization on silica

• Sodium butyrate-induced apoptosis in human colorectal cancer cell line via caspase ۹ protein

• Simultaneous effect of static magnetic field and doxorubicin on exosomal genes expression and oxidative stress in colorectal cancer cells

• The effects of DNC on proliferation and telomere in mouse fibroblasts

• microRNA-۱۴۳ inhibits metastasis of MDA-۲۳۱ breast cancer cell line

• Effect of Ergolide from inula oculus-christi on apoptosis and cell cycle mechanism in Breast cancer cell line

• Eplerenone reverses age-dependent cardiac fibrosis through downregulating osteopontin

• Evaluating expression level of miR-۱۹۶b in serum samples of hepatitis C infected individuals

• Inhibition of pathologic neovascularization using anti-VEGF diabody

• Serum levels of miR-let۷a in hepatitis C

• A gold nanoparticles biosensor for detection of miRNA-۱۲۲ in breast cancer

• Obtaining active recombinant proteins from bacterial inclusion bodies using salt solutions under neutral pH conditions

• Production of recombinant antibody against epithelial cell adhesion molecule (EpCAM) in a bacterial host and Evaluation anti-proliferative effect on breast cancer cell.

• Cytotoxic Activities of Extracts of Garlic and Green Tea

• Expressing of two antibacterial recombinant protein in E. coli showed different effect on host growth

• Investigation the effect of Thymoquinone on Sox۲ expression in a human fibroblast cell line under cobalt II chloride-induced hypoxic condition

• Evaluating the Effect of target miR-۱۰۱ transcripts (ZEB۱) Plasmid on Lung Cancer A۵۴۹ Cell Apoptosis

• Quercetin-Induced Downregulation of LncRNA UCA-۱ in MCF-۷ Cells

• Regulatory effects of miR-۲۱۸ on RIC-۳ gene expression

• Simulated Microgravity Condition Alters the Histone Gene Expression in MDA-MB-۲۳۱

• Prospects for the development of biological matrix research in line with the development of biobusiness

• An investigation into the feasibility of generating cell models for macular corneal dystrophy

• motA gene effects on expression of MALAT۱, GAS۵, NEAT۱, and PVT۱ lncRNAs in Hep G۲ cell line

• Role of CXCR۳ chemokine receptor in the development of endothelial dysfunction

• The role of vitamin D receptor in the pathogenesis of MS

• An investigation on the expression of miR-۳۴ and miR-۱۴۴ in plasma samples of RET-positive and RET-negative Medullar Thyroid Carcinoma patients

• Effect of hsa-miR-۷۶۵ on differentiation of stem cell by targeting of BAX, BAK۱ and BOK genes

• Effect of low frequency electromagnetic field on osteogenic differentiation of human adipocyte-derived mesenchymal stem cells

• Effects of Chlorella sp. and Spirulina sp. extracts on IL-۶ gene expression in broiler chickens

• Cloning of human survivin gene into pET۲۸a bacterial vector

• The study of immune system SPI۱ gene polymorphism associated with Alzheimer's Disease

• MiR-۱۴۳ inhibits migration of SW-۴۸۰ colorectal cancer cells via downregulation of MMP-۹ and ROCK

• Evaluation of glargine insulin expression using B۱ Domain of streptococcal protein G tag

• The effect of Tranilast, a TGFβ inhibitor on the colon cancer cell proliferation

• Evaluation of hsa-miR-۷۶۶-۵p as a new regulator of mitochondrial apoptosis pathway and cardiomyocyte differentiation of Human embryonic stem cells (hESCs)

• Correlation of Family history of gastric cancer with histopatological characteristics of disease in Ardabil population

• Evaluation of immunohistochemical effects of apoptotic cells in the brain and liver of chick embryos by injection of aluminosilicate

• The effect of nano Silicon on BAX expression of liver and kidney in rats

• Nanoliposome-encapsulated glutathione improves DNA fragmentation of frozen-thawed bull sperm

• Genetic Variation of Glutenin Subunits and Alleles in Iranian Wheat cultivars

• Optimization tissue culture of almond ۲-۲۲ genotype

• Identification of the flowering genes in Citrullus colocynthis L. Medicinal plant

• Study on genetic diversity of Iranian apple cultivars by SSR markers

• Expression profile of genes involved in terpene biosynthetic pathway of Mentha aquatica at different growth stages

• Characterization of a kinetochore protein "Knl۲" in Solanum lycopersicum

• Effects of Different Extraction Solvents on Total Phenolics and Flavonoids Contents and Antioxidant Activities from C. procera Hairy Root Cultures

• Study of Genetic diversity of the local rice of Hashemi variety using microsatellite markers

• Construction of plant expression vectors harboring WRI۱ gene and optimization its transformation in tobacco plants

• De novo transcriptome assembly provides insight into the specific genes of the carotenoid biosynthetic pathway of Citrullus colocynthis (L.)

• The effect of drought stress on expression of genes coding for transcription factors (ZFP۲۵۲ and DREB۲A) in rice

• Effect of mechanical stress on expression of PAL, C۴H and F۳H genes in tea leaf (Camellia sinensis)

• Evaluation of quantitative and qualitative traits of ۳۱ potato promising clones in spring cultivation

• Advances in infrageneric phylogenetics of Silene in Iran

• Bioassay for detection of glufosinate tolerant plants of Nicotiana tabacum

• Heat stress effect on the expression of some steviol biosynthesis genes in Stevia rebaudiana

• karyomorphological study of Melilotus officinalis in Iranian populations

• New insights in flowering pathway through MQTL, transcriptome profiling and CRISPR approaches in rice

• Study of morphological and genetic diversity of rice lines using microsatellite markers associated with drought tolerance traits

• Evaluation of Genetic Diversity in Bitter Vetch Based on Morphological and Agronomic Traits under Normal and Water Deficit Stress Conditions

• Evaluation and comparison of the efficiency of different molecular markers in estimating genetic distance of different Persian oak (Quercus brantii Lindi.) populations

• Chromosomal, Genome Size and Phytochemical Studies in Goji Berry (Lycium spp.) Species

• Simultaneous biochemical and molecular study of Methyl Jasmonate pathway on tolerant beans against Tetranychus urticae Koch.

• Analysis of responsive genes to nitrogen-fixing symbiotic bacteria: a systematic vs. evolutionary preview

• Expression analysis of some genes involved in lignin biosynthesis pathway under salt strees in soybean (Glycine max)

• Effect of inoculation and co-culture condition in hairy root induction in chicory (Cichorium intybus L.) by rhizogenes Agrobacterium

• The study of micropropagation in plant Glycyrrhiza glabra L.

• Molecular identification of a new isolate of Hibiscus chlorotic ringspot virus in Khuzestan province, southwestern Iran

• MAPK cascades is activated through StMAPKKKε by Phytophthora infestans infection

• The analysis of repetitive sequences in Nigella sativa and N. damascena plants

• Different reaction of citrus genotypes to Citrus yellow vein clearing virus

• Crosstalk between silicon and nitric oxide mitigates Cu stress by up-regulating of SOD gene and antioxidant enzymes activities in Salvia officinalis plants

• Generic delimitation of the genera Fragaria and Duchesnea inferred from chloroplast DNA sequence data

• The use of SSR and ISSR molecular markers to identify genetic diversity of different acid lime genotypes

• Genetic Diversity of Promised Russian Grapevine Genotype and Varieties by Using Inter Single Sequence Repeat (ISSR) DNA Marker

• Expression of a recombinant antimicrobial peptide MsDeF۱.۲ in Nicotiana tabacum

• Determination the level of genetic diversity in the rye germplasm using of ISSR and AFLP markers

• Evaluation of agronomic and biochemical traits of doubled haploid Camelina (Camelina sativa) lines under rainfed conditions

• Identification of molecular markers associated with seed vigour index of rice using recombinant inbred line population

• The effect and mechanism of mirabilis antiviral protein (MAP) of four o'clock plant on CMV (Cucumber Mosaic Virus) infections on Tobacco plant

• Effectiveness of cpDNA sequencing data trnH-psbA in classification of the genus Polygala (Polygalaceae) in Iran.

• Isolation and Sequencing of Genes Encoding Three Ficin Isoenzymes from Ficus carica Trees of Estahbanat Area of Iran

• The effect of different concentrations of nano-graphene oxide and growth regulators on proliferation, development and maturation of asexual embryos

• Establishment of Iranian Physalis alkekengi hairy roots culture by Agrobacterium rhizogenes

• Differential gene expression analysis of alkaloids production pathway in Catharanthus roseus following Salicylic acid treatment

• Positive correlation between PAL mRNA expression and enzyme activity is relation to wheat resistance induction

• Biomass accumulation and doubling time of some duckweeds native to Iran: biotechnological application

• Genomics and Transcriptomics of plant architecture in barley (Horedum vulgare L.)

• Study of structure and comparison of TRBF protein sequences in plants, using bioinformatics and computational methods

• Effects of Ethyl Methane Sulfonate on Cytogenetic Traits of Some Iranian Garlic Masses (Allium sativum L.)

• Evaluation mass poropagation of Myrobalan ۲۹c rootstock in seven different culture media

• Possible neuro-regenerative effects of ferulic acid by overexpression of anti-inflammatory markers in microglial cells

• Evaluation of MTOR gene expression alteration during adipogenesis in human mesenchymal stem cells

• The effect of electrospun zein nanofiber coated with Nano hydroxyapatite on osteogenic differentiation of mesenchymal stem cells

• Investigation of therapeutic effects of stem cell (hAMSC) on pancreatic cancer cell (MIA PaCa۲) by evaluating of epidermal growth factor receptor (EGFR) expression level

• Assessment the bioactivity and biocompatibility of nanohydroxyapatite (n-HA) coated zein nanofiber for bone tissue regeneration

• Differentiation of human adipose derived mesenchymal stem cells cultured onto compound semi-conductive Nano-fibrous scaffold into cardiomyocyte cells

• Evaluation of osteogenic differentiation of C۲C۱۲ cells on Zein and Zein/hydroxyapatite nanocomposite scaffolds