4th International & 13th Iranian Conference on Bioinformatics, بهمن ماه ۱۴۰۳

Accepted papers in 4th International & 13th Iranian Conference on Bioinformatics

• New inhibitors of the Toxoplasmosis by in -silico drug repurposing

• Leveraging Machine Learning Models for Virtual Screening of ZINC Database to Identify JAK۱ Inhibitors

• Machine Learning-Driven Discovery of JAK۲ Inhibitors from ChEMBL Databank

• Inhibition of angiogenesis based on the dynamic model of tumor growth using adaptive control method

• Discovery of effective markers in the severity of the disease in the genome of Iranian patients with covid -۱۹ and introduction of an effective plant in controlling the severity of the disease

• A Transformer-based Model for Diagnosis of Multiple Sclerosis using MRI Images

• Enhancing Drug -Target Interaction Predictions through the Integration of Self -Organizing Maps and Graph -Based Representation Learning

• Encoding the gRNA -DNA Pairs with Deep Transformers to Predict off -target Effects of CRISPR

• AI-Driven Discovery of Novel AChE Inhibitors for Alzheimer's Disease Treatment: Model Development, Molecular Docking, and MD Simulation

• The Role of Itaconate in the Advancement of Colorectal Cancer: A Mathematical Modeling Perspective

• Genetic Insights into Osteosarcoma: Implications for Targeted Drug Therapy

• In Silico Design of DNA G -Quadruplex Aptamers Targeting Lipopolysaccharide Core and Capsular Polysaccharide in Multidrug -Resistant Klebsiella pneumoniae

• Molecular Investigation of Periplasmic Sensor Histidine Kinase Interactions in Regulating UV Shield Formation of Cyanobacteria Nostoc Sp.

• Biomechanical Characterization of Realistic Bacterial Membranes Across Different Biofilm Ages: A Molecular Dynamics Study

• Investigation of the interaction of syringic acid with carbonic anhydrase using molecular docking

• A Clustering-Based Method for Preserving Manifold Structure in EEG Signals Classification

• Reconstruction and analysis of lncRNA -miRNA -mRNA ceRNA network to explore the potential biomarkers for colorectal cancer

• Identification of a natural specific inhibitor for Akt۱ protein through molecular docking studies and evaluation of DFT calculations and molecular dynamics simulations

• Investigation of the interaction between ۲-aminothiazole and bovine serum albumin (BSA), using the methods of molecular docking calculations and density functional theory (DFT)

• Molecular Docking Study of Pyrazole Interaction with Bovine Serum Albumin (BSA): Insights from Drug -Protein Binding

• Statistical Investigation on the Occurrence of Liquid -Liquid Phase Separation in Proteins Involved in Neurodegenerative Proteins

• Investigating hsa -miR -۱۴۶b and Its Targets TRAF۶ and IRAK۱ In Gastric Cancer Using Bioinformatic Tools

• Investigation and comparison of TYDC۲ gene expression in different tissues (root, leaf, capsule and petal) of medicinal plant poppy (Papaver somniferum L.) in terms of bioinformatics

• Designing Guide RNAs Considering Essential Genes for Genome Editing of Yarrowia lipolytica Using Deep Learning in the CRISPR System

• Reduced PINK۱ Expression in Bladder Cancer: Insights into Autophagy Dysregulation and Therapeutic Potential

• Enhancing the Clustering and Sorting Procedures in the MAGUS Method for Multiple Sequence Alignment

• Homology modeling and molecular docking studies for discovering FlgK protein inhibitors; Helicobacter pylori flagellar subunit.

• Molecular Docking Studies of Natural Organic Compounds against Urease of Helicobacter Pylori

• Molecular Docking Study of Natural Compounds from Daucus carota as Inhibitors of VEGFR-۲: A Computational Approach for Drug Design

• Curcumin’s Journey Through Cellulose: Binding Dynamics Across Cellulose-derived Bio-Nanofibers

• Phylogenetic and In Silico Analysis of SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) Gene Family in Crops

• Exploring the Genes Located on Chromosome Y in Non -obstructive Azoospermia: A Bioinformatic Approach

• A Computational Approach to Identify Potent Inhibitors of Janus Kinase ۱ from Natural Products: Structure-Based High-Throughput Virtual Screening and LightGBM Classifier

• Design and Analysis of siRNA for Silencing the NS۳ Gene of Hepatitis C Virus: A Novel Therapeutic Approach

• Expansion and Sequencing of the DNA Code Used in the COVID -۱۹ Vaccine Using Meta -Heuristic Algorithms

• In silico vaccine design for breast cancer

• Development of a Multi -Epitope Vaccine Candidate for Brucella: An Immunoinformatics Approach to Achieve Cross -Protection

• In silico analysis of Maize WRKY transcription factors in response to drought and salt stress

• A Fuzzy Bayesian Network Model for Personalized Diabetes Risk Prediction: Integrating Lifestyle, Genetic, and Environmental Factors

• ۳D modeling of the spike protein in the Omicron variant of the coronavirus and comparison with the Delta and Wuhan strains

• Herbal Drug Candidate as DNA Gyrase Inhibitor in M. Tuberculosis (Causative Agent of Tuberculosis)

• Bioinformatics investigation of the structure and function of photoprotein mnemiopsin۲ following Glutamine ۲۳ substitutions using a site-directed mutagenesis

• Molecular Interactions Between Vitiligo and Thyroid Diseases: Identification of Hub Genes, Pathways and Therapeutic miRNAs

• Identification of key genes associated with glioblastoma multiforme using microarray data

• A New LDA -based Genetic Algorithm for Feature Selection and Classification in Gene Expression Data Analysis

• Investigation of Missense Mutations in the SHBG Gene: Bioinformatic Analysis and Pathogenesis Prediction in binding and regulating the bioavailability of sex hormones

• In Silico Analysis of the R۴۱۰W Mutation in ZP۱: Effects on Protein Stability and Interactions

• Site-Directed Mutagenesis to Optimize Anti -TIM -۳ Antibody Affinity through In -Silico Modeling

• Assessment of TP۵۳ Gene Mutations by Bioinformatic tools and Their Impact on Tumor Suppressor Function

• Structural and Biochemical Insights into Single -Stranded DNA -Binding Protein Complexes: A Comparative Study of DnaT, DnaBC, and Pab -RPA

• Comprehensive Multi -Omics Analysis Reveals NPC۲ and ITGAV Genes as Potential Prognostic Biomarkers in Gastrointestinal Cancers

• Dysregulated genes in the fat tissue of children confer a risk of cancer

• Minimum Error Entropy: A Superior Alternative to Mean Square Error for Heavy-Tailed EEG Signal Classification

• ATIC as a Theranostic Biomarker in Gastrointestinal Cancers: Insights from Autophagy Pathway Analysis

• Enhancing NAFLD Diagnosis with AI: Insights from the Persian Fasa Cohort Through Advanced Machine Learning Techniques

• Computational study on the inhibitory potential of fungal metabolites against HIV-۱ RT

• Investigation of antiviral potency of fungal metabolites against Hepatitis C NS۵B

• Identification of potent antiviral from the fungal metabolites against SARS COV -۲ RdRp: An in silico study

• Modeling and Predicting the Use of Medications Antiplatelets and ARBs Using Logistic Regression

• BIRC۵: The silent architect of tumor persistence and senescence in Hepatocellular carcinoma

• Analysis of enrichment pathways and ontology of genes related to Feed efficiency in sheep

• Targeting Protein in Neurodegenerative Diseases: A Computational Approach

• Identification of Driver Genes in Glioblastoma Based on Single-Cell Gene Expression Data Using Integrated Pseudotime and Phylogenetic Analysis

• Bioinformatics and computational Studies on Highly Conserved Neurocalcin Protein

• Morphine pathway analysis with bioinformatics

• Multi -Target Drug Discovery for Rheumatoid Arthritis: A Comprehensive Computational Approach Using Bioactive Compounds

• HLA Class I Alleles as prognostic marker in Hepatocellular Carcinoma

• Fluidity of normal and cancer cell membranes: A molecular dynamics investigation

• Identifying mRNAs and miRNAs in extracellular vesicles through comparative transcriptome analyses of healthy and mastitic bovine milk

• Comprehensive Analysis of DCLK Family Kinases in Gastrointestinal Cancers and Neoplastic Progression

• An efficient method based on transformers for antimicrobial peptide prediction

• Bioinformatics analysis of the binding of various ligands to the acyl homoserine lactonase derived from Bacillus

• Designing Anti-Cancer Peptides Using Bioinformatics to Inhibit Survivin, Disrupt Cell Division, and Trigger Apoptosis in Cancer Cells

• Investigating the Role of EMT genes in Multiple Myeloma: A Bioinformatic Approach

• Identification of Essential Genes and Suitable Drug Combinations for Colorectal Cancer Treatment Based on Systems Biology Approaches

• Exploring the interaction between hsa -miR -۱۲۲-۵p and CDC۲۵A gene in Breast carcinoma progression via computational analysis

• Tissue-Specific Gene Co-Expression Analysis in Pediatric Ependymomas Across Different Anatomical Regions

• Exploring the Regulatory Landscape of LncRNAs in Alzheimer’s Disease: Insights into Inflammation

• High throughput screening of Plant -Derived Antimicrobial Peptides: A Peptide -Protein Docking Study Against Pathogenic Bacteria

• Novel Anti-ageing Strategy Via Targeting CST With Vitamin B۱

• Computational Analysis of the D۹۲V Mutation in the EF -hand II Loop of the Mnemiopsin ۲ Photoprotein

• In-silico Drug Generation using Masked Language Modeling

• Exploring the Anticancer Potential of Flavonoids from Morus alba Against Breast Cancer: An In Silico Approach

• A Contrastive Learning Framework for Single-Cell Multi-Omics Data Integration

• In Silico Design of a Chimeric Protein-Based Vaccine Against Salmonella Typhi: A Bioinformatics and Immunoinformatics Approach

• Bioinformatics studies on S۳۵K mutation on Mnemiopsin ۲ photoprotein

• Graphene Oxide Nanosheets as Drug Carriers for Erdafitinib in a Targeted Drug Delivery System: A Cutting-Edge Approach to Cancer Therapy

• Molecular docking study of some herbal compounds as potential inhibitors of SARS-CoV-۲ spike receptor

• Diagnosis of Diabetic Retinopathy with Fuzzy Technique and Deep Learning

• Using structural controllability to analyze signaling pathways and PPI networks for the identification of therapeutic targets in colorectal cancer

• Solving Diffusion Equations Using Physics-Informed Neural Networks: A Biological Application

• Molecular Docking Analysis of Eugenol and Paclitaxel Targeting MRAS in Breast Cancer Therapy

• Validation of Prognostic Biomarkers in Pancreatic Cancer Through Multi - Dataset Analysis and Pathway Enrichment

• Simultaneous overexpression of CD۷۰ and downregulation of CD۸۴ as a prognostic marker for glucocorticoid resistance in B cell Acute lymphoblastic leukemia

• Single-Cell Transcriptomic Analysis Reveals Cellular Heterogeneity and Molecular Markers in Acute Leukemia Subtypes

• Bioinformatics Analysis of Prostate Cancer by the Construction of circRNA -miRNA -mRNA Regulatory Network

• Uncovering Disrupted Cell-Cell Interactions in Alzheimer's Disease Using Variational Graph Autoencoders on Single-Cell Spatial Transcriptomics Data from the Human Middle Temporal Gyrus

• Comprehensive Analysis of EEG Signals for Machine Learning-Based Depression Detection

• Epitope-Based Design of a Dual-Purpose Recombinant Protein Targeting Dengue NS۱ for Vaccine and Diagnostic Development

• Integrated bioinformatic analysis for the screening of hub genes & therapeutic drugs in high-grade serous ovarian cancer

• Drug repurposing using bulk RNA-seq based on key genes involved in inflammatory bowel disease

• The key role of genes involved in proline biosynthesis and photosynthesis in drought response during Soybean flowering stage

• Predicting drug response using omics data and artificial intelligence approach in cancer

• Development of Novel Cellulose Crystal -Hyaluronic Acid Anti -Cancer Carriers for Targeting

• Potential of Lavender extract to inhibit efflux pump AdeB in multidrug resistant of Acinetobacter baumannii

• Dissecting the genetic causes of inflammatory bowel disease based on whole exome sequencing

• Iron, Oxidative Stress, and Skin Aging: The Therapeutic Potential of TGF -β۱ Modulation

• Dissecting the impact of smoking on epigenetic mechanisms that influence Lung cancer susceptibility

• The Regulatory Role of DNA Methylation in Age-Related Macular Degeneration (AMD)

• Discovering Moonlighting Proteins with AI and Explainability

• Enhancing Predictive Accuracy of CRISPR-Cas۹ on-target efficiency using Deep Learning and Active Learning Optimization for Small Datasets

• Accelerating Diffusion-Based Graph Generative Models for De Novo Drug Design via Hessian Trace Approximation

• Evaluation of Penetration Efficiency of BR۲ Peptide in Breast Cancer cell Lines Using computational Methods

• Diabetes nephropathy indicators for early diagnosis

• Predicting Adverse Drug Reactions with Advanced Machine Learning Techniques

• Elucidating Inflammatory Pathways in Polycystic Ovary Syndrome: A Transcriptomic Investigation of Granulosa Cell Gene Expression

• Investigating the role of ursolic acid in EGFR L۸۵۸R mutant inhibition in non-small cell lung cancer: Molecular docking and ADMET prediction

• Exploring the anti-inflammatory potential of the silymarin against IL-۱۷A: in silico molecular docking

• Innovative Biomarkers for Lung Cancer Classification and Prediction Using High-Dimensional Machine Learning: A Novel Approach to Targeted Therapies

• Molecular docking and bioinformatics study of active compounds of thyme) Thymus vulgaris( in inhibiting COX -۲ enzyme related to inflammatory diseases

• Novel lncRNA -miRNA -mRNA competing endogenous RNA regulatory networks in glioma

• Vaccine design for outer membrane protein C(Shigella Flexneri)

• Designing self-assembled peptide nanovaccine (SAPN) against Respiratory syncytial virus (RSV): An Immunoinformatic approach

• The inquiry of possible new candidates of inhibitors for Type IV pili of Neisseria gonorrhoeae using Molecular Docking analysis

• Identification of circRNA-miRNA-mRNA Interaction in Myocardial Infarction

• Machine-learning based biomarker discovery for Striga resistance in sorghum

• Attention based Graph Neural Network for Identifying Coding and Non-coding Breast Cancer Drivers

• Structural and Hydrogen Bonding Characteristics of Natural Deep Eutectic Solvent Choline Chloride/Citric Acid: A Molecular Dynamics Simulation Study

• Molecular Docking Study of Tromethamine and Its Analogues as Streptococcus mutans’s Enolase Inhibitors: A Novel Therapeutic Strategy

• Enzybiotic Activity in Marine Bacteria: Unveiling Cooperative and Competitive Dynamics for Antimicrobial Potential

• Comprehensive Gene and Protein Catalog for Antimicrobial Environments: A Metagenomic Approach to Mitigate Antimicrobial Resistance

• Predicting Anticancer Drug Repurposing Candidates using Knowledge Graphs

• AcrB Inhibition: A Molecular Docking Approach to Combat Escherichia coli Infections

• Comparative Analysis of Enzybiotic Gene Abundance Across Environmental Microbiomes with Varied Plastic Pollution Levels

• Gut Proteomics Reflecting Extraintestinal Organ Involvement in IBD

• Unlocking the Hidden Potential of Leuconostoc: Insights from Genomic Analysis

• A Knowledge Graph-Based Approach for Drug Repurposing Using Graph Neural Networks and Language Models

• In-silico investigation of bioactive peptides with anti-Alzheimer potential derived from bovine milk αs۱-casein protein

• Phylogenetic Insights into Enzybiotic with Novel Properties

• Boosting Healing Through Stabilized Fibrin Clot: Structural Bioinformatics Exploration of Collagen’s Potential as a Sustained-Release Carrier for Tranexamic Acid

• Exploring Vaginal Microbiome Diversity in Early Pregnancy: Implications for Healthy Pregnancy and Miscarriage

• Identification of potential RNA interference targets in bladder cancer through bioinformatics approaches

• BiogenExplorer: A Robust Solution for Rapid Gene Presence Detection and Allelic Diversity Analysis in large Genomic Datasets

• PTE -MED: AI -based Early Detection of Pulmonary Embolism

• Machine Learning for Enhanced Diagnosis of Endometriosis: Challenges and Opportunities

• Drug repurposing for brain cancer

• A computational approach to identify the biomarker based on the RNA sequencing data analysis for Alzheimer’s disease

• Prediction of E۸ mpox virus protein structure: a potential to design inhibitor

• Distribution and Allelic Diversity of Outer Membrane Proteins in Helicobacter pylori: Implications for Vaccine Development and Therapeutic Approach

• Novel Potential Peripheral ECM Biomarkers for Prognosis and Therapeutic Approaches in Liver Cirrhosis Based on Microarray Analysis

• Integrating Biological Networks and Deep Learning for Microbe -Disease Prediction

• Exploring the Antibiotic Potential of Micromonospora

• Astrocyte -Mediated Regulation of Neurogenesis in the Anterior Hippocampus of Alzheimer's Disease Patients

• Investigating the Potential of Natural Small Molecules as BDNF Mimics for Neurodegenerative Disease Treatment: A Molecular Docking Study with TrkB Receptor

• Study population structure in Iranian Arab horse breed by principal component analysis (PCA) and discriminant analysis of principal components (DAPC) methods using genomic data

• Exploring Genetic Variability: A Bioinformatics Approach to Analyzing Reported SNPs in the cagA Gene of Helicobacter pylori

• Therapeutic Biomarker Identification in Methotrexate-Treated Rheumatoid Arthritis Patients

• Comprehensive Computational Strategies for Multi -Target Drug Discovery in Inflammatory Bowel Disease Utilizing Bioactive Compounds

• A Novel Approach to Antimicrobial Susceptibility Testing: Automated Disk Diffusion Analysis with Smartphone Cameras and Deep Learning Techniques

• Age-Related Gene Expression Changes in Microglia: Insights from the Nygen platform and Brain -Aging Atlas

• Genome-Wide Bioinformatics Discovery and Validation of Long-Core SSR Markers for Alfalfa (Medicago sativa): Applications in Genetic Diversity and Seed Authentication